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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2009-3-9
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pubmed:abstractText |
Comatose survivors of out-of-hospital cardiac arrest (OHCA) have high in-hospital mortality due to a complex pathophysiology that includes cardiovascular dysfunction, inflammation, coagulopathy, brain injury and persistence of the precipitating pathology. Therapeutic hypothermia (TH) is the only intervention that has been shown to improve outcomes in this patient population. Due to the similarities between the post-cardiac arrest state and severe sepsis, it has been postulated that early goal-directed hemodyamic optimization (EGDHO) combined with TH would improve outcome of comatose cardiac arrest survivors.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0300-9572
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pubmed:author |
pubmed-author:AbellaBenjamin SBS,
pubmed-author:BandRoger ARA,
pubmed-author:BeckerLance BLB,
pubmed-author:CarrBrendan GBG,
pubmed-author:FuchsBarry DBD,
pubmed-author:GaieskiDavid FDF,
pubmed-author:GoyalMunishM,
pubmed-author:HyltonJulieJ,
pubmed-author:KlairAmandeepA,
pubmed-author:KolanskyDaniel MDM,
pubmed-author:MaguireCherylC,
pubmed-author:MerchantRaina MRM,
pubmed-author:NeumarRobert WRW
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pubmed:issnType |
Print
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pubmed:volume |
80
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
418-24
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pubmed:dateRevised |
2009-8-25
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pubmed:meshHeading |
pubmed-meshheading:19217200-Adult,
pubmed-meshheading:19217200-Aged,
pubmed-meshheading:19217200-Aged, 80 and over,
pubmed-meshheading:19217200-Algorithms,
pubmed-meshheading:19217200-Blood Gas Analysis,
pubmed-meshheading:19217200-Blood Pressure,
pubmed-meshheading:19217200-Cardiovascular Agents,
pubmed-meshheading:19217200-Clinical Protocols,
pubmed-meshheading:19217200-Cohort Studies,
pubmed-meshheading:19217200-Coma,
pubmed-meshheading:19217200-Emergency Service, Hospital,
pubmed-meshheading:19217200-Feasibility Studies,
pubmed-meshheading:19217200-Female,
pubmed-meshheading:19217200-Heart Arrest,
pubmed-meshheading:19217200-Humans,
pubmed-meshheading:19217200-Hypothermia, Induced,
pubmed-meshheading:19217200-Male,
pubmed-meshheading:19217200-Middle Aged,
pubmed-meshheading:19217200-Oxygen,
pubmed-meshheading:19217200-Retrospective Studies,
pubmed-meshheading:19217200-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
Early goal-directed hemodynamic optimization combined with therapeutic hypothermia in comatose survivors of out-of-hospital cardiac arrest.
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pubmed:affiliation |
Department of Emergency Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA. gaieskid@uphs.upenn.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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