| pubmed-article:19213879 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19213879 | lifeskim:mentions | umls-concept:C0205378 | lld:lifeskim |
| pubmed-article:19213879 | lifeskim:mentions | umls-concept:C2587213 | lld:lifeskim |
| pubmed-article:19213879 | lifeskim:mentions | umls-concept:C1450054 | lld:lifeskim |
| pubmed-article:19213879 | lifeskim:mentions | umls-concept:C0182400 | lld:lifeskim |
| pubmed-article:19213879 | lifeskim:mentions | umls-concept:C1709937 | lld:lifeskim |
| pubmed-article:19213879 | lifeskim:mentions | umls-concept:C0205171 | lld:lifeskim |
| pubmed-article:19213879 | lifeskim:mentions | umls-concept:C2699072 | lld:lifeskim |
| pubmed-article:19213879 | pubmed:issue | 5920 | lld:pubmed |
| pubmed-article:19213879 | pubmed:dateCreated | 2009-3-16 | lld:pubmed |
| pubmed-article:19213879 | pubmed:abstractText | Vesicular secretion of neurotransmitter is essential for neuronal communication. Kiss-and-run is a mode of membrane fusion and retrieval without the full collapse of the vesicle into the plasma membrane and de novo regeneration. The importance of kiss-and-run during efficient neurotransmission has remained in doubt. We developed an approach for loading individual synaptic vesicles with single quantum dots. Their size and pH-dependent photoluminescence change allowed us to distinguish kiss-and-run from full-collapse fusion and to track single vesicles through multiple rounds of kiss-and-run and reuse, without perturbing vesicle cycling. Kiss-and-run dominated at the beginning of stimulus trains, reflecting the preference of vesicles with high release probability. Its incidence was increased by rapid firing, a response appropriate to shape the kinetics of neurotransmission during a wide range of firing patterns. | lld:pubmed |
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| pubmed-article:19213879 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19213879 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19213879 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19213879 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19213879 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19213879 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:19213879 | pubmed:issn | 1095-9203 | lld:pubmed |
| pubmed-article:19213879 | pubmed:author | pubmed-author:ZhangQiQ | lld:pubmed |
| pubmed-article:19213879 | pubmed:author | pubmed-author:TsienRichard... | lld:pubmed |
| pubmed-article:19213879 | pubmed:author | pubmed-author:LiYulongY | lld:pubmed |
| pubmed-article:19213879 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19213879 | pubmed:day | 13 | lld:pubmed |
| pubmed-article:19213879 | pubmed:volume | 323 | lld:pubmed |
| pubmed-article:19213879 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19213879 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19213879 | pubmed:pagination | 1448-53 | lld:pubmed |
| pubmed-article:19213879 | pubmed:dateRevised | 2011-9-26 | lld:pubmed |
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| pubmed-article:19213879 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19213879 | pubmed:articleTitle | The dynamic control of kiss-and-run and vesicular reuse probed with single nanoparticles. | lld:pubmed |
| pubmed-article:19213879 | pubmed:affiliation | Department of Molecular and Cellular Physiology, Stanford University, Stanford, CA 94305, USA. | lld:pubmed |
| pubmed-article:19213879 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19213879 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:19213879 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
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