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rdf:type |
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lifeskim:mentions |
|
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pubmed:issue |
8
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pubmed:dateCreated |
2009-7-21
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pubmed:abstractText |
Radiotherapy of head and neck malignancies results in severe damage to salivary glands. Irradiation-induced sialadenitis with xerostomia leads to a significant deterioration of the quality of life which lasts life-long. Here we show in a preliminary study that intraglandular application of botulinum toxin performed prior to radiation reduces significantly the radiation induced toxicity of the glandular tissue in rats.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Aug
|
|
pubmed:issn |
1368-8375
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
737-9
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pubmed:meshHeading |
pubmed-meshheading:19213593-Animals,
pubmed-meshheading:19213593-Anti-Dyskinesia Agents,
pubmed-meshheading:19213593-Botulinum Toxins,
pubmed-meshheading:19213593-Disease Models, Animal,
pubmed-meshheading:19213593-Male,
pubmed-meshheading:19213593-Radiation Injuries, Experimental,
pubmed-meshheading:19213593-Radiation-Protective Agents,
pubmed-meshheading:19213593-Rats,
pubmed-meshheading:19213593-Rats, Wistar,
pubmed-meshheading:19213593-Sialadenitis,
pubmed-meshheading:19213593-Submandibular Gland
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|
pubmed:year |
2009
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|
pubmed:articleTitle |
Botulinum toxin prevents radiotherapy-induced salivary gland damage.
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pubmed:affiliation |
Department of Otolaryngology, Head and Neck Surgery, Philipp University, Marburg, Germany. teymoort@med.uni-marburg.de
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pubmed:publicationType |
Journal Article
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