Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2009-2-12
pubmed:abstractText
Positron emission tomography (PET) using [F-18]-2-deoxy-2-fluoro-D-glucose (FDG) has emerged as a promising diagnostic modality in recurrent colorectal cancer. Data in the literature show that the addition of FDG-PET changes patient management in up to 30% of patients with potentially resectable liver metastases, mainly by detecting previously unknown extrahepatic disease. Furthermore, FDG-PET is useful in the follow-up of patients who underwent surgical procedures of the liver, since it is sensitive in detecting residual or relapse malignancy in scarred liver tissue following both resection and local ablative techniques. For follow-up during systemic therapy, early FDG-PET appears predictive for response to therapy. FDG-PET, computerized tomography and magnetic resonance imaging are complementary techniques in staging and restaging patients with advanced colorectal cancer. A combination of FDG-PET and CT scanning characteristics seems promising, and integrated PET/ CT is becoming more widely available, although the exact clinical value and efficacy is not yet fully established. In addition, assessment of these modalities in joint reading sessions with radiologist, nuclear medicine physician, medical and surgical oncologists significantly impacts upon patient management. This review evaluates the potential of FDG-PET and combined PET/CT in patients with colorectal liver metastases and discusses potential future possibilities.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1421-9883
pubmed:author
pubmed:copyrightInfo
(c) 2009 S. Karger AG, Basel.
pubmed:issnType
Electronic
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
413-20
pubmed:meshHeading
pubmed-meshheading:19212113-Biopsy, Needle, pubmed-meshheading:19212113-Catheter Ablation, pubmed-meshheading:19212113-Chemotherapy, Adjuvant, pubmed-meshheading:19212113-Colorectal Neoplasms, pubmed-meshheading:19212113-Cryosurgery, pubmed-meshheading:19212113-Diagnostic Imaging, pubmed-meshheading:19212113-Female, pubmed-meshheading:19212113-Fluorodeoxyglucose F18, pubmed-meshheading:19212113-Hepatectomy, pubmed-meshheading:19212113-Humans, pubmed-meshheading:19212113-Liver Neoplasms, pubmed-meshheading:19212113-Magnetic Resonance Imaging, pubmed-meshheading:19212113-Male, pubmed-meshheading:19212113-Neoadjuvant Therapy, pubmed-meshheading:19212113-Neoplasm Staging, pubmed-meshheading:19212113-Positron-Emission Tomography, pubmed-meshheading:19212113-Preoperative Care, pubmed-meshheading:19212113-Prognosis, pubmed-meshheading:19212113-Risk Assessment, pubmed-meshheading:19212113-Sensitivity and Specificity, pubmed-meshheading:19212113-Survival Analysis, pubmed-meshheading:19212113-Tomography, X-Ray Computed, pubmed-meshheading:19212113-Treatment Outcome
pubmed:year
2008
pubmed:articleTitle
Controversies in the management of colorectal liver metastases: role of PET and PET/CT.
pubmed:affiliation
Department of Surgery, Division of Surgical Oncology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. b.wiering@chir.umcn.nl
pubmed:publicationType
Journal Article, Review