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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2009-11-2
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pubmed:abstractText |
Progression of hypertrophic cardiomyopathy (HCM) to left ventricular dilatation and systolic dysfunction sometimes occurs. However, the mechanism of the transition from hypertrophy to dysfunction has not been elucidated. It has been reported that circulating levels of monocyte chemoattractant protein-1 (MCP-1), which is a major factor promoting the accumulation of macrophages, are increased in patients with congestive heart failure. We measured circulating levels of MCP-1 in patients with HCM and examined whether MCP-1 was expressed in the myocardium of HCM patients. We also examined whether circulating levels of MCP-1 were correlated with left ventricular dysfunction.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1879-1336
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pubmed:author |
pubmed-author:BanbaKimikazuK,
pubmed-author:IwasakiJunJ,
pubmed-author:KimuraHideoH,
pubmed-author:KusanoKengo FukushimaKF,
pubmed-author:MatsubaraHiromiH,
pubmed-author:MoritaHiroshiH,
pubmed-author:MurakamiMasatoM,
pubmed-author:NagaseSatoshiS,
pubmed-author:NakamuraKazufumiK,
pubmed-author:NakamuraYoichiY,
pubmed-author:NishiiNobuhiroN,
pubmed-author:OheTohruT,
pubmed-author:Ohta-OgoKeikoK,
pubmed-author:OkaTakefumiT,
pubmed-author:TohNorihisaN
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pubmed:issnType |
Electronic
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
317-22
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pubmed:meshHeading |
pubmed-meshheading:19211266-Cardiomyopathy, Hypertrophic,
pubmed-meshheading:19211266-Chemokine CCL2,
pubmed-meshheading:19211266-Disease Progression,
pubmed-meshheading:19211266-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:19211266-Female,
pubmed-meshheading:19211266-Humans,
pubmed-meshheading:19211266-Immunohistochemistry,
pubmed-meshheading:19211266-Male,
pubmed-meshheading:19211266-Middle Aged,
pubmed-meshheading:19211266-Myocardium,
pubmed-meshheading:19211266-Ventricular Dysfunction, Left
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pubmed:articleTitle |
Relationship between circulating levels of monocyte chemoattractant protein-1 and systolic dysfunction in patients with hypertrophic cardiomyopathy.
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pubmed:affiliation |
Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Shikata-cho, Okayama, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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