Source:http://linkedlifedata.com/resource/pubmed/id/19209316
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
2009-2-11
|
| pubmed:abstractText |
We report that the hydrogen-bonding pattern in a molecular beacon can be replaced by metal-dependent pairs of Hg(2+) and DNA thymine (T) bases. A molecular beacon based on T-Hg(2+)-T exhibits a lower background signal and higher thermostability than regular molecular beacons.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
1359-7345
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
21
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
322-4
|
| pubmed:meshHeading |
pubmed-meshheading:19209316-Base Sequence,
pubmed-meshheading:19209316-DNA Probes,
pubmed-meshheading:19209316-Fluorescent Dyes,
pubmed-meshheading:19209316-Kinetics,
pubmed-meshheading:19209316-Mercury,
pubmed-meshheading:19209316-Nucleic Acid Hybridization,
pubmed-meshheading:19209316-Thermodynamics,
pubmed-meshheading:19209316-Thymine
|
| pubmed:year |
2009
|
| pubmed:articleTitle |
Reversible molecular switching of molecular beacon: controlling DNA hybridization kinetics and thermodynamics using mercury(ii) ions.
|
| pubmed:affiliation |
State Key Lab of Chemo/Biosensing and Chemometrics, Biomedical Engineering Center, College of Chemistry and Chemical Engineering, Hunan University, Changsa, 410082, China. Yangrh@pku.edu.cn
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|