Source:http://linkedlifedata.com/resource/pubmed/id/19208499
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2009-7-31
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pubmed:abstractText |
Acetylcholine induced inwardly rectifying current (I(KACh)) is a heteromultimeric complex formed by Kir3.1 and Kir3.4 subunits and plays important roles in the development of atrial fibrillation (AF). AF is a common disorder among Chinese, the frequency of AF is about 0.61%, and in patients with strokes it is 12.1%. We hypothesise that lone paroxysmal AF genetic variation in Kir3.4 may predispose the atria to fibrillation in the Chinese population.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1444-2892
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
257-61
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pubmed:meshHeading |
pubmed-meshheading:19208499-Adult,
pubmed-meshheading:19208499-Atrial Fibrillation,
pubmed-meshheading:19208499-Case-Control Studies,
pubmed-meshheading:19208499-China,
pubmed-meshheading:19208499-Female,
pubmed-meshheading:19208499-G Protein-Coupled Inwardly-Rectifying Potassium Channels,
pubmed-meshheading:19208499-Gene Frequency,
pubmed-meshheading:19208499-Genotype,
pubmed-meshheading:19208499-Humans,
pubmed-meshheading:19208499-Male,
pubmed-meshheading:19208499-Middle Aged,
pubmed-meshheading:19208499-Odds Ratio,
pubmed-meshheading:19208499-Polymorphism, Single Nucleotide
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pubmed:year |
2009
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pubmed:articleTitle |
The single nucleotide polymorphisms of Kir3.4 gene and their correlation with lone paroxysmal atrial fibrillation in Chinese Han population.
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pubmed:affiliation |
Department of Cardiovascular Internal Medicine, Huzhou Central Hospital, Huzhou, Zhejiang Province, China. Zhangchuan1973@yahoo.cn
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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