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rdf:type |
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lifeskim:mentions |
umls-concept:C0001645,
umls-concept:C0018801,
umls-concept:C0087111,
umls-concept:C0205191,
umls-concept:C0542560,
umls-concept:C0681850,
umls-concept:C1550501,
umls-concept:C1706203,
umls-concept:C1821417,
umls-concept:C2349001,
umls-concept:C2697811
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pubmed:issue |
1
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pubmed:dateCreated |
2009-2-11
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pubmed:abstractText |
We investigated the relationship between resting heart rate (HR) and two measures of beta-1 receptor sensitivity/blockade: (1) the percentage of maximal predicted heart rate reached during exercise (%MPHR), and (2) the HR increase per unit of circulating norepinephrine (NE) or the chronotropic responsiveness index (CRI) in 28 patients with systolic CHF on chronic beta-blocker therapy. Our results show that resting HR is not associated with HR response during exercise nor with beta-1 receptor sensitivity to circulating NE.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1755-5914
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
42-8
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:19207479-Adrenergic beta-1 Receptor Antagonists,
pubmed-meshheading:19207479-Adrenergic beta-Antagonists,
pubmed-meshheading:19207479-Adult,
pubmed-meshheading:19207479-Biological Markers,
pubmed-meshheading:19207479-Chronic Disease,
pubmed-meshheading:19207479-Exercise Test,
pubmed-meshheading:19207479-Exercise Tolerance,
pubmed-meshheading:19207479-Female,
pubmed-meshheading:19207479-Heart Failure,
pubmed-meshheading:19207479-Heart Rate,
pubmed-meshheading:19207479-Humans,
pubmed-meshheading:19207479-Male,
pubmed-meshheading:19207479-Middle Aged,
pubmed-meshheading:19207479-Norepinephrine,
pubmed-meshheading:19207479-Practice Guidelines as Topic,
pubmed-meshheading:19207479-Treatment Outcome
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pubmed:year |
2009
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pubmed:articleTitle |
Resting heart rate does not reflect the degree of beta-blockade in subjects with heart failure on chronic beta-blocker therapy.
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pubmed:affiliation |
Department of Medicine, Division of Cardiology, Columbia University Medical Center, New York, NY 10032, USA.
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pubmed:publicationType |
Journal Article
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