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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2009-2-11
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pubmed:abstractText |
Introduction: It is known that warfarin treatment is problematic, due to its narrow therapeutic range and to the great interindividual variability. Numerous papers have shown the important contribution of CYP2C9 and VKORC1 genetic variants to this variability. Recently, a new SNP within the CYP4F2 gene was found associated with warfarin dose in the USA.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1744-8042
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
261-6
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pubmed:meshHeading |
pubmed-meshheading:19207028-Aged,
pubmed-meshheading:19207028-Anticoagulants,
pubmed-meshheading:19207028-Atrial Fibrillation,
pubmed-meshheading:19207028-Cohort Studies,
pubmed-meshheading:19207028-Cytochrome P-450 Enzyme System,
pubmed-meshheading:19207028-DNA,
pubmed-meshheading:19207028-Dose-Response Relationship, Drug,
pubmed-meshheading:19207028-Female,
pubmed-meshheading:19207028-Genetic Variation,
pubmed-meshheading:19207028-Genotype,
pubmed-meshheading:19207028-Heart Valve Prosthesis Implantation,
pubmed-meshheading:19207028-Humans,
pubmed-meshheading:19207028-Italy,
pubmed-meshheading:19207028-Male,
pubmed-meshheading:19207028-Mixed Function Oxygenases,
pubmed-meshheading:19207028-Rome,
pubmed-meshheading:19207028-Venous Thrombosis,
pubmed-meshheading:19207028-Warfarin
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pubmed:year |
2009
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pubmed:articleTitle |
CYP4F2 genetic variant (rs2108622) significantly contributes to warfarin dosing variability in the Italian population.
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pubmed:affiliation |
Department of Biopathology and Diagnostic Imaging, School of Medicine, Tor Vergata University, Rome, Italy. borgiani@uniroma2.it
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pubmed:publicationType |
Journal Article
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