rdf:type |
|
lifeskim:mentions |
umls-concept:C0002736,
umls-concept:C0026809,
umls-concept:C0042776,
umls-concept:C0086418,
umls-concept:C0270764,
umls-concept:C0332307,
umls-concept:C1314792,
umls-concept:C1512704,
umls-concept:C1552603,
umls-concept:C1706202,
umls-concept:C2348205
|
pubmed:issue |
19
|
pubmed:dateCreated |
1977-5-25
|
pubmed:abstractText |
In certain genetically susceptible populations of wild mice a progressive motor neuron disease with a long latent period is caused by indigenous type C leukemia virus. Neuronal damage appears to be due primarily to a direct neurotropic effect of the virus and not to an immunogenic mechanism. The disease can be prevented by antiviral genetic means. Search for a similar virus in humans with ALS has been negative.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0082-7134
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
217-34
|
pubmed:dateRevised |
2009-11-11
|
pubmed:meshHeading |
pubmed-meshheading:191966-Amyotrophic Lateral Sclerosis,
pubmed-meshheading:191966-Animals,
pubmed-meshheading:191966-Anterior Horn Cells,
pubmed-meshheading:191966-Antibodies, Viral,
pubmed-meshheading:191966-Antigens, Viral,
pubmed-meshheading:191966-Genes,
pubmed-meshheading:191966-Humans,
pubmed-meshheading:191966-Immunosuppression,
pubmed-meshheading:191966-Inclusion Bodies, Viral,
pubmed-meshheading:191966-Lymphoma,
pubmed-meshheading:191966-Mice,
pubmed-meshheading:191966-Paralysis,
pubmed-meshheading:191966-Retroviridae,
pubmed-meshheading:191966-Rodent Diseases,
pubmed-meshheading:191966-Vacuoles,
pubmed-meshheading:191966-Virus Diseases
|
pubmed:year |
1976
|
pubmed:articleTitle |
Lower motor neuron disease in wild mice caused by indigenous type C virus and search for a similar etiology in human amyotrophic lateral sclerosis.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|