19196117

Source:http://linkedlifedata.com/resource/pubmed/id/19196117

Download in:

Switch to

Custom View

Named Graph Language Inference

Statements in which the resource exists as a subject.
Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0007301, umls-concept:C0038250, umls-concept:C0185125, umls-concept:C0545661, umls-concept:C0596171
pubmed:issue	2
pubmed:dateCreated	2010-4-9
pubmed:abstractText	The adipose tissue was considered a reserve of energy until the '80s, when it was found that this tissue was involved in the metabolism of sex steroids such as estrogens. From then on, the importance attributed to this tissue radically changed as it was then considered an active organ, involved in important functions of the human body. In 2001, for the first time, the existence of stem cells within this tissue was reported, and since then, this tissue has been gaining an increased importance as a stem cell source for a wide range of potential applications in cell therapies and/or tissue engineering and regenerative medicine strategies, mainly due to its wide availability and easy access. This manuscript provides an overview on adipose stem cells (i.e., adipose tissue-derived stem cells, ASCs) considering the tissue of origin, the niche of the ASCs, and their phenotype in all aspects. In this paper it is also discussed the markers that have been used for the characterization of these cells, their differentiation properties, and their immunological reactivity, reporting studies from 2001 until this date. The ASCs are also compared with bone marrow stem cells (BMSCs), until now considered as the gold standard source of stem cells, underlining the common characteristics and the differences between the stem cells obtained from these two sources, as well as the advantages and disadvantages of their potential use in different applications. Finally, this review will also focus on the potential application of ASCs in tissue engineering applications, particularly in the regeneration of bone and cartilage, commenting on the progress of this approach and future trends of the field.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101466660
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:month	Jun
pubmed:issn	1937-3376
pubmed:author	pubmed-author:GomesManuela EME, pubmed-author:RadaTommasoT, pubmed-author:ReisRui LRL
pubmed:issnType	Electronic
pubmed:volume	15
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	113-25
pubmed:meshHeading	pubmed-meshheading:19196117-Adipose Tissue, pubmed-meshheading:19196117-Bone and Bones, pubmed-meshheading:19196117-Cartilage, pubmed-meshheading:19196117-Humans, pubmed-meshheading:19196117-Stem Cells, pubmed-meshheading:19196117-Tissue Engineering
pubmed:year	2009
pubmed:articleTitle	Adipose tissue-derived stem cells and their application in bone and cartilage tissue engineering.
pubmed:affiliation	3B's Research Group-Biomaterials, Biodegradables and Biomimetics, Department of Polymer Engineering, University of Minho, Braga, Portugal.
pubmed:publicationType	Journal Article, Review, Research Support, Non-U.S. Gov't