|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1
|
|
pubmed:dateCreated |
1991-11-21
|
|
pubmed:abstractText |
In a prospective study, we analysed the presence of monoclonal immunoglobulin (moIg) in the serum from 30 patients with amyotrophic lateral sclerosis (ALS) and 30 matched controls using a sensitive Western blot technique. The incidence of serum moIg was 60% in the ALS group and 13.3% in the control group. Most ALS sera contained 2 or 3 monoclonal components. They were IgG (72.7%) and IgM (27.3%). These results corroborate the concept of a probable association between ALS and serum moIg.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
0022-510X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
104
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
88-91
|
|
pubmed:dateRevised |
2004-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:1919600-Adolescent,
pubmed-meshheading:1919600-Adult,
pubmed-meshheading:1919600-Aged,
pubmed-meshheading:1919600-Amyotrophic Lateral Sclerosis,
pubmed-meshheading:1919600-Antibodies, Monoclonal,
pubmed-meshheading:1919600-Blotting, Western,
pubmed-meshheading:1919600-Child,
pubmed-meshheading:1919600-Electrophoresis, Agar Gel,
pubmed-meshheading:1919600-Female,
pubmed-meshheading:1919600-Humans,
pubmed-meshheading:1919600-Immunoelectrophoresis,
pubmed-meshheading:1919600-Immunoglobulins,
pubmed-meshheading:1919600-Male,
pubmed-meshheading:1919600-Middle Aged,
pubmed-meshheading:1919600-Motor Neurons,
pubmed-meshheading:1919600-Spinal Cord
|
|
pubmed:year |
1991
|
|
pubmed:articleTitle |
Quantitative analysis of monoclonal immunoglobulins in serum of patients with amyotrophic lateral sclerosis.
|
|
pubmed:affiliation |
Laboratoire d'Immunologie et d'Immunopathologie, UA 1172 CNRS, Hôpital de la Milétrie, Poitiers, France.
|
|
pubmed:publicationType |
Journal Article
|
