Source:http://linkedlifedata.com/resource/pubmed/id/19195685
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2009-8-31
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pubmed:abstractText |
It is considered that high plasma levels of procarboxypeptidase U (proCPU or TAFI) can promote the development of thrombosis, but data comparing proCPU levels in thrombophilia carriers and healthy subjects are rather scarce. Moreover, the results of previous studies on the risk of thrombosis related to high proCPU concentration in this population were not consistent. Although the 325 polymorphism of proCPU has a significant effect on the CPU half-life, it's influence on the risk of thrombosis or spontaneous pregnancy loss in carriers of hereditary thrombophilia is not clear.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1879-2472
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
124
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
427-32
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pubmed:meshHeading |
pubmed-meshheading:19195685-Adult,
pubmed-meshheading:19195685-Carboxypeptidase U,
pubmed-meshheading:19195685-Female,
pubmed-meshheading:19195685-Genetic Predisposition to Disease,
pubmed-meshheading:19195685-Humans,
pubmed-meshheading:19195685-Male,
pubmed-meshheading:19195685-Mutation,
pubmed-meshheading:19195685-Polymorphism, Genetic,
pubmed-meshheading:19195685-Prothrombin,
pubmed-meshheading:19195685-Thrombophilia,
pubmed-meshheading:19195685-Thrombosis
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pubmed:year |
2009
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pubmed:articleTitle |
Procarboxypeptidase U (TAFI) contributes to the risk of thrombosis in patients with hereditary thrombophilia.
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pubmed:affiliation |
Laboratory of Medical Biochemistry, University of Antwerp, Antwerp, Belgium.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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