Linked Life Data

19195624

Source:http://linkedlifedata.com/resource/pubmed/id/19195624

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6 Pt 2
pubmed:dateCreated
2009-2-6
pubmed:abstractText
In patients with diabetes and metabolic syndrome, liver changes may be observed on histology that are characterized as non-alcoholic fatty liver disease (NAFLD). The NAFLD spectrum covers a variety of histological features, including steatosis, necroinflammation and fibrosis. Although steatosis usually follows a benign course, steatohepatitis is prone to progress to fibrosis and cirrhosis. Establishing the degree of severity of liver lesions, the main endpoint of the disease, can identify patients at risk of disease progression. This may be achieved by liver biopsy. For that purpose, a scoring system for both activity (grade) and fibrosis (stage) is available with good reproducibility. In addition to the commonly seen histopathological patterns of lesions, additional changes are reported in patients with diabetes, including glycogenic hepatopathy and hepatic hepatosclerosis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1262-3636
pubmed:author
pubmed:issnType
Print
pubmed:volume
34
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
638-42
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Definition and natural history of metabolic steatosis: histology and cellular aspects.
pubmed:affiliation
Pathology Department, Beaujon hospital Clichy, 92118 Clichy cedex, France. vparadis@teaser.fr
pubmed:publicationType
Journal Article, Review