Source:http://linkedlifedata.com/resource/pubmed/id/19194192
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2009-2-5
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pubmed:abstractText |
We investigated obesity [body mass index (BMI) >95th percentile] and being heavy (BMI >85th percentile) in 95 children in first remission more than 2 years after treatment for acute lymphoblastic leukemia or non-Hodgkin lymphoma seen at our institution. Height, weight and BMI at diagnosis, end of treatment and follow-up, and blood pressure at diagnosis were adjusted by z-score for age and sex. At follow-up, obesity and overweight were not more prevalent than in the general population. Median BMI z-scores rose significantly between diagnosis (0.38) and treatment end (0.62) but not during follow-up (0.70). Median weight z-scores rose significantly during both periods (diagnosis 0.23, treatment end 0.49, and follow-up 0.68). Median height z-scores were 0.51, 0.14, and 0.16 for the same 3 time points, respectively. Repeated measures, multivariate logistic regression identified Hispanic ethnicity, younger age at diagnosis, and a positive age:weight interaction as being associated with obesity and being heavy at follow-up. There was no association with diagnosis, sex, age alone, radiation dose or field, metabolic diagnosis in patient/family, height z-score at diagnosis, duration of treatment, and systolic or diastolic blood pressure. Obesity and overweight were a combination of weight gain and height loss during treatment although weight continued to increase after treatment. We did not identify disease-related parameters associated with these effects.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1536-3678
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
101-7
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pubmed:dateRevised |
2011-10-6
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pubmed:meshHeading |
pubmed-meshheading:19194192-Adolescent,
pubmed-meshheading:19194192-Body Height,
pubmed-meshheading:19194192-Body Mass Index,
pubmed-meshheading:19194192-Child,
pubmed-meshheading:19194192-Child, Preschool,
pubmed-meshheading:19194192-Female,
pubmed-meshheading:19194192-Follow-Up Studies,
pubmed-meshheading:19194192-Humans,
pubmed-meshheading:19194192-Infant,
pubmed-meshheading:19194192-Lymphoma, Non-Hodgkin,
pubmed-meshheading:19194192-Male,
pubmed-meshheading:19194192-Obesity,
pubmed-meshheading:19194192-Precursor Cell Lymphoblastic Leukemia-Lymphoma,
pubmed-meshheading:19194192-Prevalence,
pubmed-meshheading:19194192-Risk Factors,
pubmed-meshheading:19194192-Survivors,
pubmed-meshheading:19194192-Time Factors,
pubmed-meshheading:19194192-Weight Gain
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pubmed:year |
2009
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pubmed:articleTitle |
Risk factors for the development of obesity in children surviving ALL and NHL.
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pubmed:affiliation |
Department of Pediatrics, University of California, Davis School of Medicine, CA, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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