19188864

Source:http://linkedlifedata.com/resource/pubmed/id/19188864

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0016059, umls-concept:C0021467, umls-concept:C0021469, umls-concept:C0030274, umls-concept:C0037083, umls-concept:C0040690, umls-concept:C0062095, umls-concept:C0199176, umls-concept:C0695347, umls-concept:C1710082
pubmed:issue	4
pubmed:dateCreated	2009-4-24
pubmed:abstractText	Chronic pancreatitis is characterized by inflammation and fibrosis. We evaluated the efficacy of halofuginone, an inhibitor of collagen synthesis and myofibroblast activation, in preventing cerulein-induced pancreas fibrosis.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8608542
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Caerulein, http://linkedlifedata.com/resource/pubmed/chemical/Collagen, http://linkedlifedata.com/resource/pubmed/chemical/Extracellular Signal-Regulated MAP..., http://linkedlifedata.com/resource/pubmed/chemical/Globins, http://linkedlifedata.com/resource/pubmed/chemical/Pap protein, mouse, http://linkedlifedata.com/resource/pubmed/chemical/Piperidines, http://linkedlifedata.com/resource/pubmed/chemical/Procollagen-Proline Dioxygenase, http://linkedlifedata.com/resource/pubmed/chemical/Protein Disulfide-Isomerases, http://linkedlifedata.com/resource/pubmed/chemical/Protein Synthesis Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Quinazolinones, http://linkedlifedata.com/resource/pubmed/chemical/Serum Response Factor, http://linkedlifedata.com/resource/pubmed/chemical/Smad3 Protein, http://linkedlifedata.com/resource/pubmed/chemical/Smad3 protein, mouse, http://linkedlifedata.com/resource/pubmed/chemical/Tissue Inhibitor of..., http://linkedlifedata.com/resource/pubmed/chemical/Transforming Growth Factor beta, http://linkedlifedata.com/resource/pubmed/chemical/cytoglobin, http://linkedlifedata.com/resource/pubmed/chemical/halofuginone
pubmed:status	MEDLINE
pubmed:month	May
pubmed:issn	1536-4828
pubmed:author	pubmed-author:GeninOlgaO, pubmed-author:HalevyOrnaO, pubmed-author:IovannaJuan LJL, pubmed-author:KawadaNorifumiN, pubmed-author:NaglerArnonA, pubmed-author:PinesMarkM, pubmed-author:RoffeSuzyS, pubmed-author:YoshizatoKatsutoshiK, pubmed-author:ZionOritO
pubmed:issnType	Electronic
pubmed:volume	38
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	427-35
pubmed:dateRevised	2009-11-19
pubmed:meshHeading	pubmed-meshheading:19188864-Animals, pubmed-meshheading:19188864-Blotting, Western, pubmed-meshheading:19188864-Caerulein, pubmed-meshheading:19188864-Cells, Cultured, pubmed-meshheading:19188864-Collagen, pubmed-meshheading:19188864-Extracellular Matrix, pubmed-meshheading:19188864-Extracellular Signal-Regulated MAP Kinases, pubmed-meshheading:19188864-Fibrosis, pubmed-meshheading:19188864-Globins, pubmed-meshheading:19188864-Immunohistochemistry, pubmed-meshheading:19188864-In Situ Hybridization, pubmed-meshheading:19188864-Injections, Intraperitoneal, pubmed-meshheading:19188864-Male, pubmed-meshheading:19188864-Mice, pubmed-meshheading:19188864-Mice, Inbred ICR, pubmed-meshheading:19188864-Pancreas, pubmed-meshheading:19188864-Piperidines, pubmed-meshheading:19188864-Procollagen-Proline Dioxygenase, pubmed-meshheading:19188864-Protein Disulfide-Isomerases, pubmed-meshheading:19188864-Protein Synthesis Inhibitors, pubmed-meshheading:19188864-Proteins, pubmed-meshheading:19188864-Quinazolinones, pubmed-meshheading:19188864-Serum Response Factor, pubmed-meshheading:19188864-Signal Transduction, pubmed-meshheading:19188864-Smad3 Protein, pubmed-meshheading:19188864-Tissue Inhibitor of Metalloproteinases, pubmed-meshheading:19188864-Transforming Growth Factor beta
pubmed:year	2009
pubmed:articleTitle	Inhibition of transforming growth factor beta signaling by halofuginone as a modality for pancreas fibrosis prevention.
pubmed:affiliation	Institute of Animal Sciences, The Volcani Center, Bet Dagan, Israel.
pubmed:publicationType	Journal Article