Linked Life Data

1918821

Source:http://linkedlifedata.com/resource/pubmed/id/1918821

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1991-11-6
pubmed:abstractText
Proliferative vitreoretinopathy (PVR) is a major complication of rhegmatogenous retinal detachment. Its pathogenesis remains poorly understood and the accurate nature of the growing cells on both surfaces of the detached retina has not been yet determined. We undertook an immunocytological study on 28 specimens of vitreous or subretinal fluid removed from patients with PVR. Five main types of cells could be identified: heavily pigmented cells, poorly pigmented ones, large totally unpigmented macrophage-like ones, smaller unpigmented cells and lymphocytes. Analysis of intravitreal pigment granules showed two different types of pigmented cells, those with lipofuscin and melanin and those with melanin without any granules of lipofuscin, which could originate from ciliary or iris pigment epithelia. Immunostaining procedures confirmed the epithelial non macrophagic lineage of the intravitreal and subretinal cells. Lymphocytes were only B cells. These results confirm the importance of proliferative process during the course of PVR and shows the involvement of other ocular structures other than the retinal pigment epithelium.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0181-5512
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
147-52
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
[Immunomorphological study of the vitreous body and subretinal fluid in vitreoretinal proliferation].
pubmed:affiliation
Service d'Ophtalmologie, Hôpital Saint-Roch, Nice.
pubmed:publicationType
Journal Article, English Abstract