Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2009-4-21
pubmed:abstractText
Extensive variations of colloid osmotic pressure (COP) measured in the priming as well as during infant cardiopulmonary bypass motivated us to audit clinical and laboratory data to identify the risk factors for low COP at the end of bypass. Data of 73 consecutive infant patients with body weight <10 kg, who underwent elective, first time open-heart surgery between March 2005 and December 2006 were examined. The following variables were analyzed: COP, blood loss, transfusion requirements and hematological data. Univariate and multivariate analysis of risk factors for low COP (<15 mmHg) was performed. Forty-eight percent of patients had COP <15 mmHg at the end of bypass. Those patients had significantly lower COP before start of bypass, during, and at the end of the operation. Significant univariate predictors of low COP at the end of bypass were: lower patient weight; lower COP before start of bypass, lower priming COP and larger volume of cardioplegia received into the circulation. After multivariable analysis, lower patient COP before bypass remained the only significant predictor for low COP at the end of bypass. Pre-bypass crystalloid dilution during induction should be avoided, as this is the most important cause of low COP during the bypass. Priming COP and COP management strategy should be adapted to the individual patient demand.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1569-9285
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
512-6
pubmed:meshHeading
pubmed-meshheading:19188213-Body Weight, pubmed-meshheading:19188213-Cardiac Surgical Procedures, pubmed-meshheading:19188213-Cardioplegic Solutions, pubmed-meshheading:19188213-Cardiopulmonary Bypass, pubmed-meshheading:19188213-Colloids, pubmed-meshheading:19188213-Female, pubmed-meshheading:19188213-Heart Arrest, Induced, pubmed-meshheading:19188213-Hemodilution, pubmed-meshheading:19188213-Humans, pubmed-meshheading:19188213-Infant, pubmed-meshheading:19188213-Male, pubmed-meshheading:19188213-Osmotic Pressure, pubmed-meshheading:19188213-Patient Selection, pubmed-meshheading:19188213-Potassium Compounds, pubmed-meshheading:19188213-Retrospective Studies, pubmed-meshheading:19188213-Risk Assessment, pubmed-meshheading:19188213-Risk Factors, pubmed-meshheading:19188213-Time Factors, pubmed-meshheading:19188213-Treatment Outcome
pubmed:year
2009
pubmed:articleTitle
Risk factors for low colloid osmotic pressure during infant cardiopulmonary bypass with a colloidal prime.
pubmed:affiliation
Department of Cardiothoracic Surgery, Erasmus MC, University Medical Center Rotterdam, 's Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands. h.golab-schwarz@erasmusmc.nl
pubmed:publicationType
Journal Article