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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2009-2-17
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pubmed:abstractText |
We investigated the relationship between hypertriglyceridemia and the single-nucleotide polymorphisms (SNPs) on APOA5 in human immunodeficiency virus (HIV)-infected patients receiving highly active antiretroviral therapy (HAART) in Taiwan. Receipt of protease inhibitor-based HAART, high baseline triglyceride levels, and carriage of APOA5 SNP3 or c.553G>T variants or APOA5 SNP1T/SNP2G/SNP3C/c.553T haplotype were statistically significantly associated with development of extreme hypertriglyceridemia (triglyceride level, >500 mg/dL).
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1537-6591
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pubmed:author |
pubmed-author:ChangLan-YangLY,
pubmed-author:ChangShan-ChwenSC,
pubmed-author:ChangShu-FangSF,
pubmed-author:ChangSui-YuanSY,
pubmed-author:ChenMao-YuanMY,
pubmed-author:HsiehSzu-MinSM,
pubmed-author:HsuHui-JenHJ,
pubmed-author:HungChien-ChingCC,
pubmed-author:KaoChuan-LiangCL,
pubmed-author:KaoJau-TsuenJT,
pubmed-author:KoWei-ShinWS,
pubmed-author:LeeChun-NanCN,
pubmed-author:LiuWen-ChunWC,
pubmed-author:ShengWang-HueiWH,
pubmed-author:SunHsin-YunHY,
pubmed-author:WuCheng-HsinCH
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pubmed:issnType |
Electronic
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pubmed:day |
15
|
|
pubmed:volume |
48
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
832-5
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pubmed:meshHeading |
pubmed-meshheading:19187029-Adult,
pubmed-meshheading:19187029-Aged,
pubmed-meshheading:19187029-Aged, 80 and over,
pubmed-meshheading:19187029-Antiretroviral Therapy, Highly Active,
pubmed-meshheading:19187029-Apolipoproteins A,
pubmed-meshheading:19187029-Female,
pubmed-meshheading:19187029-HIV Infections,
pubmed-meshheading:19187029-HIV Protease Inhibitors,
pubmed-meshheading:19187029-Haplotypes,
pubmed-meshheading:19187029-Humans,
pubmed-meshheading:19187029-Hypertriglyceridemia,
pubmed-meshheading:19187029-Male,
pubmed-meshheading:19187029-Middle Aged,
pubmed-meshheading:19187029-Point Mutation,
pubmed-meshheading:19187029-Polymorphism, Single Nucleotide,
pubmed-meshheading:19187029-Taiwan,
pubmed-meshheading:19187029-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
Association of single-nucleotide polymorphism 3 and c.553G>T of APOA5 with hypertriglyceridemia after treatment with highly active antiretroviral therapy containing protease inhibitors in hiv-infected individuals in Taiwan.
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pubmed:affiliation |
Department of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University College of Medicine, Taipei, Taiwan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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