rdf:type |
|
lifeskim:mentions |
umls-concept:C0001779,
umls-concept:C0004083,
umls-concept:C0007222,
umls-concept:C0009566,
umls-concept:C0011854,
umls-concept:C0014257,
umls-concept:C0021368,
umls-concept:C0023981,
umls-concept:C0127400,
umls-concept:C0332281,
umls-concept:C0441889,
umls-concept:C0597357,
umls-concept:C0910022,
umls-concept:C1749467,
umls-concept:C1848822,
umls-concept:C2603343
|
pubmed:issue |
4
|
pubmed:dateCreated |
2009-2-27
|
pubmed:abstractText |
Plasma soluble receptor for AGE (sRAGE) may reflect the activity of the AGE-RAGE axis, which has been proposed as a potential mechanism linking hyperglycaemia to vascular complications in diabetes. We have therefore investigated: (1) whether sRAGE is associated with greater prevalence of cardiovascular disease (CVD) and microvascular complications in type 1 diabetic individuals; and (2) the extent to which any such associations are explained by markers of endothelial and renal dysfunction and inflammation.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
1432-0428
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
52
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
705-14
|
pubmed:dateRevised |
2011-11-17
|
pubmed:meshHeading |
pubmed-meshheading:19183936-Adolescent,
pubmed-meshheading:19183936-Adult,
pubmed-meshheading:19183936-Cardiovascular Diseases,
pubmed-meshheading:19183936-Diabetes Mellitus, Type 1,
pubmed-meshheading:19183936-Diabetic Angiopathies,
pubmed-meshheading:19183936-Endothelium, Vascular,
pubmed-meshheading:19183936-Female,
pubmed-meshheading:19183936-Humans,
pubmed-meshheading:19183936-Inflammation,
pubmed-meshheading:19183936-Insulin,
pubmed-meshheading:19183936-Kidney,
pubmed-meshheading:19183936-Male,
pubmed-meshheading:19183936-Middle Aged,
pubmed-meshheading:19183936-Multicenter Studies as Topic,
pubmed-meshheading:19183936-Receptors, Immunologic,
pubmed-meshheading:19183936-Risk Factors,
pubmed-meshheading:19183936-Young Adult
|
pubmed:year |
2009
|
pubmed:articleTitle |
Levels of soluble receptor for AGE are cross-sectionally associated with cardiovascular disease in type 1 diabetes, and this association is partially mediated by endothelial and renal dysfunction and by low-grade inflammation: the EURODIAB Prospective Complications Study.
|
pubmed:affiliation |
Care and Public Health Research Institute (CAPHRI), Maastricht University Medical Centre, Maastricht, the Netherlands. j.nin@intmed.unimaas.nl
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|