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rdf:type |
|
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lifeskim:mentions |
umls-concept:C0007226,
umls-concept:C0008059,
umls-concept:C0014406,
umls-concept:C0017337,
umls-concept:C0042333,
umls-concept:C0087178,
umls-concept:C0239307,
umls-concept:C0314603,
umls-concept:C0441889,
umls-concept:C0489835,
umls-concept:C1280500,
umls-concept:C1418779,
umls-concept:C1542147,
umls-concept:C1704675,
umls-concept:C2603343
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|
pubmed:issue |
4
|
|
pubmed:dateCreated |
2009-2-27
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|
pubmed:abstractText |
The PPARGC1A gene coactivates multiple nuclear transcription factors involved in cellular energy metabolism and vascular stasis. In the present study, we genotyped 35 tagging polymorphisms to capture all common PPARGC1A nucleotide sequence variations and tested for association with metabolic and cardiovascular traits in 2,101 Danish and Estonian boys and girls from the European Youth Heart Study, a multicentre school-based cross-sectional cohort study.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Apr
|
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pubmed:issn |
1432-0428
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pubmed:author |
|
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pubmed:issnType |
Electronic
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
609-13
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:19183932-Adolescent,
pubmed-meshheading:19183932-Amino Acid Sequence,
pubmed-meshheading:19183932-Blood Pressure,
pubmed-meshheading:19183932-Body Mass Index,
pubmed-meshheading:19183932-Cardiovascular Diseases,
pubmed-meshheading:19183932-Child,
pubmed-meshheading:19183932-Environment,
pubmed-meshheading:19183932-Europe,
pubmed-meshheading:19183932-Female,
pubmed-meshheading:19183932-Genetic Variation,
pubmed-meshheading:19183932-Heat-Shock Proteins,
pubmed-meshheading:19183932-Humans,
pubmed-meshheading:19183932-Insulin,
pubmed-meshheading:19183932-Life Style,
pubmed-meshheading:19183932-Linkage Disequilibrium,
pubmed-meshheading:19183932-Male,
pubmed-meshheading:19183932-Motor Activity,
pubmed-meshheading:19183932-Obesity,
pubmed-meshheading:19183932-Overweight,
pubmed-meshheading:19183932-Physical Fitness,
pubmed-meshheading:19183932-Polymorphism, Genetic,
pubmed-meshheading:19183932-Polymorphism, Single Nucleotide,
pubmed-meshheading:19183932-Risk Factors,
pubmed-meshheading:19183932-Transcription Factors
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pubmed:year |
2009
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pubmed:articleTitle |
PPARGC1A sequence variation and cardiovascular risk-factor levels: a study of the main genetic effects and gene x environment interactions in children from the European Youth Heart Study.
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pubmed:affiliation |
Genetic Epidemiology and Clinical Research Group, Department of Public Health and Clinical Medicine, Umeå University Hospital, Medicine Clinic, Level 4, Stair B, Umeå, 901 87, Sweden.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study
|
