Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2009-1-30
pubmed:abstractText
Studies on molecular structure and mechanisms of replication of a pathogen are important from both scientific and clinical viewpoints. The replication study allows us to identify key molecules to regulate life cycle of the pathogen and to screen rationally anti-pathogen drugs. The structural study helps understand how the key molecules work at atomic levels and to design adequately the drugs. In this article, we review important findings on structural and replication studies of human immunodeficiency virus (HIV). We also summarize the latest methods for the structural study, mainly focusing on computational simulation technology (in silico analysis). Finally, we summarize briefly standard methods to study replication of viruses.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0047-1852
pubmed:author
pubmed:issnType
Print
pubmed:volume
67
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
37-42
pubmed:dateRevised
2011-7-27
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
[Structure and molecular mechanisms of infection and replication of HIV].
pubmed:affiliation
Laboratory of Viral Genomics, Center for Pathogen Genomics, National Institute of Infectious Diseases.
pubmed:publicationType
Journal Article, English Abstract, Review