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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1991-11-13
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pubmed:abstractText |
This study was conducted to obtain additional information about the adaptations after 12 wk of high-fat diet (HFD) per se or HFD combined with endurance training in the rat using a two [diet: carbohydrate (CHO) or HFD] by two (training: sedentary or trained) by two (condition at death: rested or exercised) factorial design. Adaptation to prolonged HFD increases maximal O2 uptake (VO2max; 13%, P less than 0.05) and submaximal running endurance (+64%, P less than 0.05). This enhancement in exercise capacity could be attributed to 1) an increase in skeletal muscle aerobic enzyme activities (3-hydroxyacyl-CoA dehydrogenase and citrate synthase in soleus and red quadriceps) or 2) a decrease in liver glycogen breakdown in response to 1 h exercise at 80% VO2max. When training is superimposed to HFD, the most prominent finding provided by this study is that the diet-induced effects are cumulative with the well-known training effect on VO2max, exercise endurance, oxidative capacity of red muscle, and metabolic responses to exercise, with a further reduction in liver glycogen breakdown.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
8750-7587
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
71
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
197-203
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:1917743-Animals,
pubmed-meshheading:1917743-Body Weight,
pubmed-meshheading:1917743-Diet,
pubmed-meshheading:1917743-Dietary Carbohydrates,
pubmed-meshheading:1917743-Dietary Fats,
pubmed-meshheading:1917743-Energy Metabolism,
pubmed-meshheading:1917743-Glucose,
pubmed-meshheading:1917743-Glycolysis,
pubmed-meshheading:1917743-Liver,
pubmed-meshheading:1917743-Liver Glycogen,
pubmed-meshheading:1917743-Male,
pubmed-meshheading:1917743-Muscles,
pubmed-meshheading:1917743-Oxygen Consumption,
pubmed-meshheading:1917743-Physical Conditioning, Animal,
pubmed-meshheading:1917743-Rats,
pubmed-meshheading:1917743-Rats, Inbred Strains
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pubmed:year |
1991
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pubmed:articleTitle |
Additive effects of training and high-fat diet on energy metabolism during exercise.
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pubmed:affiliation |
Laboratoire de Physiologie, Faculté de Médecine, Unité de Recherche Associée 1341 Centre National de la Recherche Scientifique, Lyon, France.
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pubmed:publicationType |
Journal Article
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