|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0007578,
umls-concept:C0007634,
umls-concept:C0017262,
umls-concept:C0021083,
umls-concept:C0036667,
umls-concept:C0086418,
umls-concept:C0185117,
umls-concept:C0312418,
umls-concept:C0334227,
umls-concept:C0346647,
umls-concept:C0598077,
umls-concept:C1317964,
umls-concept:C1322652,
umls-concept:C1511545,
umls-concept:C1536403,
umls-concept:C1707689,
umls-concept:C2911684
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2009-8-3
|
|
pubmed:abstractText |
gammadelta-T cells can recognize and kill malignant cells, particularly those of epithelial origin, through mechanisms which do not require the recognition of tumor-specific antigens (innate immune response). This natural ability of gammadelta-T cells to kill tumor cells in a tumor antigen-independent manner provides a strong rationale for developing clinical trials designed to exploit the innate antitumor properties of gammadelta-T cells.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD11,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD18,
http://linkedlifedata.com/resource/pubmed/chemical/Cell Adhesion Molecules,
http://linkedlifedata.com/resource/pubmed/chemical/Histocompatibility Antigens Class I,
http://linkedlifedata.com/resource/pubmed/chemical/ICAM2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Intercellular Adhesion Molecule-1,
http://linkedlifedata.com/resource/pubmed/chemical/MHC class I-related chain A,
http://linkedlifedata.com/resource/pubmed/chemical/MICB antigen,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Antigen, T-Cell...
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
1440-1746
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
24
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
900-11
|
|
pubmed:meshHeading |
pubmed-meshheading:19175829-Antigens, CD,
pubmed-meshheading:19175829-Antigens, CD11,
pubmed-meshheading:19175829-Antigens, CD18,
pubmed-meshheading:19175829-Cell Adhesion,
pubmed-meshheading:19175829-Cell Adhesion Molecules,
pubmed-meshheading:19175829-Cell Line, Tumor,
pubmed-meshheading:19175829-Coculture Techniques,
pubmed-meshheading:19175829-Cytotoxicity, Immunologic,
pubmed-meshheading:19175829-Histocompatibility Antigens Class I,
pubmed-meshheading:19175829-Humans,
pubmed-meshheading:19175829-Immunity, Innate,
pubmed-meshheading:19175829-Immunotherapy,
pubmed-meshheading:19175829-Intercellular Adhesion Molecule-1,
pubmed-meshheading:19175829-Pancreatic Neoplasms,
pubmed-meshheading:19175829-Receptors, Antigen, T-Cell, gamma-delta,
pubmed-meshheading:19175829-T-Lymphocytes,
pubmed-meshheading:19175829-Transfection
|
|
pubmed:year |
2009
|
|
pubmed:articleTitle |
Expression of intercellular adhesion molecule (ICAM)-1 or ICAM-2 is critical in determining sensitivity of pancreatic cancer cells to cytolysis by human gammadelta-T cells: implications in the design of gammadelta-T-cell-based immunotherapies for pancreatic cancer.
|
|
pubmed:affiliation |
Division of Hematology and Oncology, Department of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama 35294, USA.
|
|
pubmed:publicationType |
Journal Article
|
