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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2009-1-27
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pubmed:abstractText |
Obstructive uropathy is argued to involve an ischemia-type tissue injury. Further, hypoxia-inducible factor 1 alpha (HIF-1 alpha) constitutes a nuclear transcription factor normally upregulated under hypoxic conditions. We hypothesized that HIF-1 alpha is expressed in the hydronephrotic renal pelvis, as a result of tissue hypoxia.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1423-0399
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pubmed:author |
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pubmed:copyrightInfo |
(c) 2009 S. Karger AG, Basel.
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pubmed:issnType |
Electronic
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pubmed:volume |
82
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
38-42
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pubmed:meshHeading |
pubmed-meshheading:19172095-Adult,
pubmed-meshheading:19172095-Anoxia,
pubmed-meshheading:19172095-Case-Control Studies,
pubmed-meshheading:19172095-Female,
pubmed-meshheading:19172095-Fibroblasts,
pubmed-meshheading:19172095-Humans,
pubmed-meshheading:19172095-Hydronephrosis,
pubmed-meshheading:19172095-Hyperplasia,
pubmed-meshheading:19172095-Hypertrophy,
pubmed-meshheading:19172095-Hypoxia-Inducible Factor 1, alpha Subunit,
pubmed-meshheading:19172095-Immunohistochemistry,
pubmed-meshheading:19172095-Kidney Pelvis,
pubmed-meshheading:19172095-Male,
pubmed-meshheading:19172095-Middle Aged,
pubmed-meshheading:19172095-Muscle, Smooth,
pubmed-meshheading:19172095-Nephrectomy,
pubmed-meshheading:19172095-Prospective Studies,
pubmed-meshheading:19172095-Stromal Cells,
pubmed-meshheading:19172095-Up-Regulation,
pubmed-meshheading:19172095-Urothelium
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pubmed:year |
2009
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pubmed:articleTitle |
Hydronephrosis promotes expression of hypoxia-inducible factor 1 alpha.
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pubmed:affiliation |
1st Urology Department, Laiko General Hospital, Athens, Greece.
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pubmed:publicationType |
Journal Article
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