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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2009-4-28
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pubmed:abstractText |
Caffeine, an antagonist of adenosine A(1) and A(2A) receptor, is the most widely used psychoactive substance in the world. Evidence indicates that caffeine interacts with the neuronal systems involved in drug reinforcing. Although adenosine A(1) and/or A(2A) receptor have been found to play important roles in the locomotor stimulation and probably reinforcing effect of caffeine, the relative contribution of the A(1) and/or A(2A) receptors to the acute and chronic motor activation and reinforcing effects of caffeine has not been completely investigated.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/1,3-dipropyl-8-cyclopentylxanthine,
http://linkedlifedata.com/resource/pubmed/chemical/5-amino-7-(2-phenylethyl)-2-(2-furyl...,
http://linkedlifedata.com/resource/pubmed/chemical/Adenosine A2 Receptor Antagonists,
http://linkedlifedata.com/resource/pubmed/chemical/Caffeine,
http://linkedlifedata.com/resource/pubmed/chemical/Dopamine and cAMP-Regulated...,
http://linkedlifedata.com/resource/pubmed/chemical/Neuroprotective Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphodiesterase Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Ppp1r1b protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Purinergic P1 Receptor Antagonists,
http://linkedlifedata.com/resource/pubmed/chemical/Pyrimidines,
http://linkedlifedata.com/resource/pubmed/chemical/Triazoles,
http://linkedlifedata.com/resource/pubmed/chemical/Xanthines
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1432-2072
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
204
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
313-25
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:19169672-Adenosine A2 Receptor Antagonists,
pubmed-meshheading:19169672-Animals,
pubmed-meshheading:19169672-Blotting, Western,
pubmed-meshheading:19169672-Caffeine,
pubmed-meshheading:19169672-Conditioning, Operant,
pubmed-meshheading:19169672-Dopamine and cAMP-Regulated Phosphoprotein 32,
pubmed-meshheading:19169672-Dose-Response Relationship, Drug,
pubmed-meshheading:19169672-Male,
pubmed-meshheading:19169672-Mice,
pubmed-meshheading:19169672-Mice, Inbred C57BL,
pubmed-meshheading:19169672-Neuroprotective Agents,
pubmed-meshheading:19169672-Phosphodiesterase Inhibitors,
pubmed-meshheading:19169672-Purinergic P1 Receptor Antagonists,
pubmed-meshheading:19169672-Pyrimidines,
pubmed-meshheading:19169672-Reward,
pubmed-meshheading:19169672-Triazoles,
pubmed-meshheading:19169672-Xanthines
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pubmed:year |
2009
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pubmed:articleTitle |
Caffeine and a selective adenosine A2A receptor antagonist induce reward and sensitization behavior associated with increased phospho-Thr75-DARPP-32 in mice.
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pubmed:affiliation |
Department of Emergency Medicine, Tzu Chi General Hospital, Hualien 970, Taiwan. saab30002000@yahoo.com.tw
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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