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pubmed-article:19169270pubmed:abstractTextThe aim of this study was to design and synthesize a series of high activity compounds against aspartyl protease beta-secretase (BACE-1) bearing hydroxyethylene (HE) framework.lld:pubmed
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pubmed-article:19169270pubmed:articleTitleDiscovery of potent beta-secretase (bace-1) inhibitors by the synthesis of isophthalamide-containing hybrids.lld:pubmed
pubmed-article:19169270pubmed:affiliationThe State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.lld:pubmed
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