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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2009-8-21
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pubmed:databankReference |
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pubmed:abstractText |
Preclinical studies suggest that inhibition of vascular endothelial growth factor (VEGF) improves glioma response to radiotherapy. Bevacizumab, a monoclonal antibody against VEGF, has shown promise in recurrent gliomas, but the safety and efficacy of concurrent bevacizumab with brain irradiation has not been extensively studied. The objectives of this study were to determine the safety and activity of this combination in malignant gliomas.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1879-355X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
75
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
156-63
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:19167838-Adult,
pubmed-meshheading:19167838-Aged,
pubmed-meshheading:19167838-Aged, 80 and over,
pubmed-meshheading:19167838-Angiogenesis Inhibitors,
pubmed-meshheading:19167838-Antibodies, Monoclonal,
pubmed-meshheading:19167838-Antibodies, Monoclonal, Humanized,
pubmed-meshheading:19167838-Astrocytoma,
pubmed-meshheading:19167838-Brain Neoplasms,
pubmed-meshheading:19167838-Combined Modality Therapy,
pubmed-meshheading:19167838-Disease-Free Survival,
pubmed-meshheading:19167838-Dose Fractionation,
pubmed-meshheading:19167838-Female,
pubmed-meshheading:19167838-Glioblastoma,
pubmed-meshheading:19167838-Humans,
pubmed-meshheading:19167838-Male,
pubmed-meshheading:19167838-Middle Aged,
pubmed-meshheading:19167838-Neoplasm Recurrence, Local,
pubmed-meshheading:19167838-Radiosurgery,
pubmed-meshheading:19167838-Vascular Endothelial Growth Factor A
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pubmed:year |
2009
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pubmed:articleTitle |
Safety and efficacy of bevacizumab with hypofractionated stereotactic irradiation for recurrent malignant gliomas.
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pubmed:affiliation |
Department of Neurosurgery, The Brain Tumor Center, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA. gutinp@mskcc.org
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pubmed:publicationType |
Journal Article,
Evaluation Studies
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