Source:http://linkedlifedata.com/resource/pubmed/id/19165130
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2009-3-2
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pubmed:abstractText |
Twenty-six Thai HIV-infected children, aged 2 years or less were prospectively enrolled to receive non-nucleoside reverse transcription inhibitor-based highly active antiretroviral therapy (HAART). Twenty-two children (85%) had World Health Organization clinical stage 3 or 4. The median baseline CD4 cell percentage and plasma HIV RNA were 17% and 5.9 log 10 copies/mL, respectively. The median age at HAART initiation was 9.8 months (range, 1.5-24.0). One child died. The mean CD4 cell percentages at 24, 48, and 96 weeks of treatment were 26%, 31%, and 37%, respectively. The proportions of children with virologic suppression (<400 copies/mL) at week 24 and 48 were 14/26 (54%) and 19/26 (73%), respectively. Non-nucleoside reverse transcription inhibitor-based HAART is safe and effective in HIV-infected young children in a resource-limited setting.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anti-HIV Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Lamivudine,
http://linkedlifedata.com/resource/pubmed/chemical/Nevirapine,
http://linkedlifedata.com/resource/pubmed/chemical/Reverse Transcriptase Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Stavudine
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0891-3668
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
246-8
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pubmed:meshHeading |
pubmed-meshheading:19165130-Anti-HIV Agents,
pubmed-meshheading:19165130-Antiretroviral Therapy, Highly Active,
pubmed-meshheading:19165130-Drug Therapy, Combination,
pubmed-meshheading:19165130-Female,
pubmed-meshheading:19165130-HIV Infections,
pubmed-meshheading:19165130-HIV-1,
pubmed-meshheading:19165130-Humans,
pubmed-meshheading:19165130-Infant,
pubmed-meshheading:19165130-Lamivudine,
pubmed-meshheading:19165130-Male,
pubmed-meshheading:19165130-Nevirapine,
pubmed-meshheading:19165130-Reverse Transcriptase Inhibitors,
pubmed-meshheading:19165130-Stavudine,
pubmed-meshheading:19165130-Thailand,
pubmed-meshheading:19165130-Treatment Outcome
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pubmed:year |
2009
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pubmed:articleTitle |
Efficacy of non-nucleoside reverse transcriptase inhibitor-based highly active antiretroviral therapy in Thai HIV-infected children aged two years or less.
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pubmed:affiliation |
Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
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