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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2009-2-11
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pubmed:abstractText |
Eicosapentaenoic acid (EPA) has been known as a reagent for improving lipid metabolism and inflammation. Hepatocyte-specific Pten-deficient mice exhibit hepatic lesions analogous to non-alcoholic steatohepatitis (NASH). Therefore, we administered EPA to Pten-deficient mice to investigate the mechanisms of NASH.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0168-8278
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pubmed:author |
pubmed-author:AnezakiYumikoY,
pubmed-author:DohmenTakahiroT,
pubmed-author:GotoTakashiT,
pubmed-author:HorieYasuoY,
pubmed-author:IshiiHajimeH,
pubmed-author:KataokaEiE,
pubmed-author:KinoshitaNobukatsuN,
pubmed-author:OhnishiHirohideH,
pubmed-author:OhshimaShigetoshiS,
pubmed-author:SasakiJunkoJ,
pubmed-author:SasakiTakehikoT,
pubmed-author:SatoWataruW,
pubmed-author:SuzukiAkiraA,
pubmed-author:WatanabeSumioS
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pubmed:issnType |
Print
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
562-71
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:19162361-Animals,
pubmed-meshheading:19162361-Carcinoma, Hepatocellular,
pubmed-meshheading:19162361-Eicosapentaenoic Acid,
pubmed-meshheading:19162361-Fatty Liver,
pubmed-meshheading:19162361-Liver Neoplasms,
pubmed-meshheading:19162361-Mice,
pubmed-meshheading:19162361-Mice, Knockout,
pubmed-meshheading:19162361-Mitogen-Activated Protein Kinases,
pubmed-meshheading:19162361-PTEN Phosphohydrolase,
pubmed-meshheading:19162361-Reactive Oxygen Species
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pubmed:year |
2009
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pubmed:articleTitle |
Eicosapentaenoic acid ameliorates steatohepatitis and hepatocellular carcinoma in hepatocyte-specific Pten-deficient mice.
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pubmed:affiliation |
Department of Gastroenterology, Akita University School of Medicine, Akita, Japan.
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pubmed:publicationType |
Journal Article
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