|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1
|
|
pubmed:dateCreated |
2009-2-16
|
|
pubmed:abstractText |
Understanding the molecular factors that distinguish inflammatory breast cancer (IBC) from non-IBC is important for IBC diagnosis. We reviewed the records of 48 IBC patients and 64 non-IBC patients from Egypt. We determined RhoC expression and tumor emboli and their relationship to demographic and reproductive characteristics. Compared with non-IBC patients, IBC patients had significantly lower parity (P=0.018) and fewer palpable tumors (P<0.0001). IBC tumors showed RhoC overexpression more frequently than non-IBC tumors (87% vs. 17%, respectively) (P<0.0001). Tumor emboli were significantly more frequent in IBC tumors than non-IBC tumors (Mean+/- SD: 14.1+/-14.0 vs. 7.0+/-12.9, respectively) (P<0.0001). This study illustrates that RhoC overexpression and tumor emboli are more frequent in tumors of IBC relative to non-IBC from Egypt. Future studies should focus on relating epidemiologic factors to molecular features of IBC in this population.
|
|
pubmed:grant |
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19157876-10499627,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19157876-11194451,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19157876-11250736,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19157876-11839578,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19157876-12854690,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19157876-14999149,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19157876-14999150,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19157876-15203457,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19157876-15305401,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19157876-15998949,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19157876-16187229,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19157876-16198566,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19157876-18058225,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19157876-9635529,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19157876-9850015
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
1532-3080
|
|
pubmed:author |
pubmed-author:BanerjeeMousumiM,
pubmed-author:DouglasJulie AJA,
pubmed-author:EissaSaadS,
pubmed-author:GeorgopoulosAgelikiA,
pubmed-author:HablasAhmedA,
pubmed-author:KhaledHusseinH,
pubmed-author:KleerCelina GCG,
pubmed-author:LoAn-ChiAC,
pubmed-author:MerajverSofia DSD,
pubmed-author:OmarHoda GHG,
pubmed-author:OmarSherifS,
pubmed-author:SolimanAmr SAS
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
18
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
55-9
|
|
pubmed:dateRevised |
2011-9-26
|
|
pubmed:meshHeading |
pubmed-meshheading:19157876-Adult,
pubmed-meshheading:19157876-Aged,
pubmed-meshheading:19157876-Breast Neoplasms,
pubmed-meshheading:19157876-Carcinoma, Ductal, Breast,
pubmed-meshheading:19157876-Carcinoma, Lobular,
pubmed-meshheading:19157876-Egypt,
pubmed-meshheading:19157876-Female,
pubmed-meshheading:19157876-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:19157876-Humans,
pubmed-meshheading:19157876-Logistic Models,
pubmed-meshheading:19157876-Middle Aged,
pubmed-meshheading:19157876-Molecular Epidemiology,
pubmed-meshheading:19157876-Neoplastic Cells, Circulating,
pubmed-meshheading:19157876-Parity,
pubmed-meshheading:19157876-Pregnancy,
pubmed-meshheading:19157876-Retrospective Studies,
pubmed-meshheading:19157876-rho GTP-Binding Proteins
|
|
pubmed:year |
2009
|
|
pubmed:articleTitle |
Analysis of RhoC expression and lymphovascular emboli in inflammatory vs non-inflammatory breast cancers in Egyptian patients.
|
|
pubmed:affiliation |
Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA.
|
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|
