Source:http://linkedlifedata.com/resource/pubmed/id/19150314
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2009-1-19
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pubmed:abstractText |
Coagulopathy is an essential component of the acute liver failure (ALF) syndrome and reflects the central role of liver function in hemostasis. ALF is a syndrome characterized by the development of hepatic encephalopathy and coagulopathy within 24 weeks of the onset of acute liver disease. Coagulopathy in this setting is a useful prognostic tool in ALF and a dynamic indicator of the hepatic function. If severe, it can be associated with bleeding and is commonly a major obstacle to the performance of invasive procedures in patients with ALF. This review focuses on the epidemiology, pathophysiology, presentation, evaluation, and management of coagulopathy in ALF.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1557-8224
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
95-107
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pubmed:meshHeading |
pubmed-meshheading:19150314-Blood Coagulation Disorders,
pubmed-meshheading:19150314-Disease Progression,
pubmed-meshheading:19150314-Hemorrhage,
pubmed-meshheading:19150314-Humans,
pubmed-meshheading:19150314-International Normalized Ratio,
pubmed-meshheading:19150314-Liver Failure, Acute,
pubmed-meshheading:19150314-Liver Transplantation,
pubmed-meshheading:19150314-Postoperative Hemorrhage
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pubmed:year |
2009
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pubmed:articleTitle |
Coagulopathy of acute liver failure.
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pubmed:affiliation |
University of Pennsylvania, School of Medicine, 3400 Spruce Street, Philadelphia, PA 19104, USA. Santiago.Munoz@uphs.upenn.edu
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pubmed:publicationType |
Journal Article,
Review
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