Source:http://linkedlifedata.com/resource/pubmed/id/19150171
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
2009-7-29
|
| pubmed:abstractText |
The authors present the first case report of complete histologic remission after neoadjuvant sunitinib treatment on primary renal tumour and vena cava thrombus. A 78-yr-old woman with an Eastern Cooperative Oncology Group (ECOG) score of 0 presented with a T3b renal tumour. She refused surgical treatment but agreed to percutaneous biopsy and medical treatment. A Fuhrman III renal cell carcinoma was histologically confirmed on percutaneous biopsy, and sunitinib treatment was administered over 6 mo. A significant objective response was observed for tumour size and thrombus. The patient finally accepted surgical treatment. Pathologic examination concluded with a complete response of primary tumour and thrombus.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
1873-7560
|
| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:volume |
55
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1477-80
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| pubmed:meshHeading |
pubmed-meshheading:19150171-Aged,
pubmed-meshheading:19150171-Biopsy, Needle,
pubmed-meshheading:19150171-Carcinoma, Renal Cell,
pubmed-meshheading:19150171-Dose-Response Relationship, Drug,
pubmed-meshheading:19150171-Drug Administration Schedule,
pubmed-meshheading:19150171-Female,
pubmed-meshheading:19150171-Follow-Up Studies,
pubmed-meshheading:19150171-Humans,
pubmed-meshheading:19150171-Immunohistochemistry,
pubmed-meshheading:19150171-Indoles,
pubmed-meshheading:19150171-Kidney Neoplasms,
pubmed-meshheading:19150171-Magnetic Resonance Imaging,
pubmed-meshheading:19150171-Neoadjuvant Therapy,
pubmed-meshheading:19150171-Neoplasm Staging,
pubmed-meshheading:19150171-Nephrectomy,
pubmed-meshheading:19150171-Protein Kinase Inhibitors,
pubmed-meshheading:19150171-Pyrroles,
pubmed-meshheading:19150171-Treatment Outcome
|
| pubmed:year |
2009
|
| pubmed:articleTitle |
Case study of the month. Complete histologic remission after sunitinib neoadjuvant therapy in T3b renal cell carcinoma.
|
| pubmed:affiliation |
Bordeaux University Hospital, Department of Urology, Bordeaux, France. gregoire.robert@chu-bordeaux.fr
|
| pubmed:publicationType |
Journal Article,
Case Reports
|