Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2009-1-16
pubmed:abstractText
Cherney and co-workers examine the functional phenotype of the G894T eNOS polymorphism in a selected group of apparently healthy subjects. The investigators used L-arginine infusion and induced changes in renal hemodynamics. While L-arginine increased effective plasma flow and glomerular filtration rate in GG subjects, these responses were blunted in GT/TT subjects, suggesting that either the G894T polymorphism impairs eNOS function, or GG subjects exhibit augmented eNOS responsiveness to L-arginine. The complexity of this seemingly straightforward conclusion deserves elaboration.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1523-1755
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
75
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
255-7
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Endothelial nitric oxide synthase: from structure to function in one aspartic substitution.
pubmed:affiliation
Department of Medicine, Renal Research Institute, New York Medical College, Valhalla, New York 10595, USA. michael_goligorsky@nymc.edu
pubmed:publicationType
Journal Article, Comment