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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2009-1-15
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pubmed:abstractText |
Biocompatibility of porous granulated bioceramic materials (hydroxyapatite, beta-tricalcium phosphate, hydroxyapatite-b-tricalcium phosphate complex (80:20 wt%), carbonate-containing hydroxyapatite, and silicon-containing hydroxyapatite) was shown in a subcutaneous test on BDF1 mice. Dynamic (up to 8 months) observation showed gradual replacement of the granular substance with de novo forming bone tissue with hemopoiesis foci on a model of fenestral defect in the shin bone in Wistar rats. By the rate of resorption, the materials rank as follows: silicon-containing hydroxyapatite<hydroxyapatite<hydroxyapatite-beta-tricalcium phosphate<beta-tricalcium phosphate<carbonate-containing hydroxyapatite. The rate of resorption in bone tissue defect was significantly higher than in the subcutaneous test, but lagged behind (even for tricalcium phosphate and carbonate-containing hydroxyapatite) bone tissue formation de novo.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0007-4888
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pubmed:author |
pubmed-author:AchmedovaS ASA,
pubmed-author:BarinovS MSM,
pubmed-author:ChissovV IVI,
pubmed-author:FadeevaI VIV,
pubmed-author:FiljushinM MMM,
pubmed-author:FrankG AGA,
pubmed-author:KirsanovaV AVA,
pubmed-author:KomlevV SVS,
pubmed-author:ReshetovI VIV,
pubmed-author:SergeevaN SNS,
pubmed-author:SviridovaI KIK
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pubmed:issnType |
Print
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pubmed:volume |
146
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
139-43
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pubmed:meshHeading |
pubmed-meshheading:19145372-Animals,
pubmed-meshheading:19145372-Biocompatible Materials,
pubmed-meshheading:19145372-Calcium Phosphates,
pubmed-meshheading:19145372-Ceramics,
pubmed-meshheading:19145372-Hydroxyapatites,
pubmed-meshheading:19145372-Implants, Experimental,
pubmed-meshheading:19145372-Materials Testing,
pubmed-meshheading:19145372-Mice,
pubmed-meshheading:19145372-Porosity,
pubmed-meshheading:19145372-Rats,
pubmed-meshheading:19145372-Rats, Wistar,
pubmed-meshheading:19145372-Tibia
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pubmed:year |
2008
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pubmed:articleTitle |
Study of in vivo biocompatibility and dynamics of replacement of rat shin defect with porous granulated bioceramic materials.
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pubmed:affiliation |
P. A. Hertzen Moscow Oncological Institute, Rosmedtechnologies, Moscow, Russia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Evaluation Studies
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