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pubmed-article:1914487pubmed:abstractTextThere is a marked decrease of the right ventricular ejection fraction after the administration of a bolus of endotoxin to sheep. This hemodynamic response may be the result of thromboxane-mediated pulmonary hypertension. Right ventricular function was studied in an ovine model after the administration of endotoxin (1 microgram/kg Escherichia coli) with and without pretreatment with OKY-046, a selective thromboxane synthetase inhibitor.lld:pubmed
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pubmed-article:1914487pubmed:dateRevised2007-11-15lld:pubmed
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pubmed-article:1914487pubmed:articleTitleInhibition of thromboxane synthesis reduces endotoxin-induced right ventricular failure in sheep.lld:pubmed
pubmed-article:1914487pubmed:affiliationDepartment of Anesthesiology, University of Texas Medical Branch, Galveston.lld:pubmed
pubmed-article:1914487pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:1914487pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed