Source:http://linkedlifedata.com/resource/pubmed/id/19144396
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
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| pubmed:dateCreated |
2009-3-9
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| pubmed:abstractText |
The objective was to investigate the feasibility of improving embryo yield in superovulated cows following insemination with sex-sorted semen by prior immunization against inhibin. Twenty-eight heifers were allocated into three groups: High (n=10), Low (n=10), and Control (n=8). The High group received one primary (1mg) and two booster (0.5mg) vaccinations (28-d intervals) with a recombinant inhibin alpha-subunit in 1 mL of white oil adjuvant, whereas the Low group received half that dose, and the Control group received only adjuvant. After the last immunization, all heifers underwent a standard superovulation treatment (decreasing doses of pFSH for 4d), followed by two AI with 2 x 10(6) sex-sorted semen after the onset of estrus. Inhibin-immunized heifers had higher (P<0.01) plasma antibody titres, and an earlier onset of estrus (P<0.05) than Control heifers. The total number of embryo/ova, transferable, and grade 1 embryos in the High group (15.4+/-1.9, 5.7+/-0.7, and 3.8+/-1.0, respectively) was significantly greater than that of the Control group (9.1+/-1.2, 3.1+/-0.5, and 0.6+/-0.2), but was intermediate (P>0.05) in the Low group (13.0+/-2.3, 4.4+/-0.7, and 1.2+/-0.3). There were no significant differences among groups in number of unfertilized ova and degenerated embryos. The High group also had higher (P>0.05) plasma progesterone concentrations on the day of embryo collection. In conclusion, immunization against inhibin improved both embryo quantity and quality following superovulation and insemination with sex-sorted semen.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies,
http://linkedlifedata.com/resource/pubmed/chemical/Estradiol,
http://linkedlifedata.com/resource/pubmed/chemical/Follicle Stimulating Hormone,
http://linkedlifedata.com/resource/pubmed/chemical/Inhibins,
http://linkedlifedata.com/resource/pubmed/chemical/Progesterone,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/inhibin-alpha subunit
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| pubmed:status |
MEDLINE
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| pubmed:month |
Apr
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| pubmed:issn |
0093-691X
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
1
|
| pubmed:volume |
71
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1011-7
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| pubmed:dateRevised |
2010-11-18
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| pubmed:meshHeading |
pubmed-meshheading:19144396-Animals,
pubmed-meshheading:19144396-Antibodies,
pubmed-meshheading:19144396-Cattle,
pubmed-meshheading:19144396-Cell Separation,
pubmed-meshheading:19144396-Estradiol,
pubmed-meshheading:19144396-Estrus,
pubmed-meshheading:19144396-Female,
pubmed-meshheading:19144396-Follicle Stimulating Hormone,
pubmed-meshheading:19144396-Immunization,
pubmed-meshheading:19144396-Immunization, Secondary,
pubmed-meshheading:19144396-Inhibins,
pubmed-meshheading:19144396-Insemination, Artificial,
pubmed-meshheading:19144396-Male,
pubmed-meshheading:19144396-Pregnancy,
pubmed-meshheading:19144396-Progesterone,
pubmed-meshheading:19144396-Recombinant Proteins,
pubmed-meshheading:19144396-Sex Determination Analysis,
pubmed-meshheading:19144396-Spermatozoa,
pubmed-meshheading:19144396-Superovulation
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| pubmed:year |
2009
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| pubmed:articleTitle |
Immunization against inhibin enhances both embryo quantity and quality in Holstein heifers after superovulation and insemination with sex-sorted semen.
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| pubmed:affiliation |
Department of Animal Science, South China Agricultural University, Guangzhou 510642, China.
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| pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|