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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2009-3-16
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pubmed:abstractText |
Phosphodiesterase 5 inhibitors (PDE5) such as sildenafil are first-line treatment for erectile dysfunction (ED). Alpha1 (alpha1)-adrenoceptor antagonists such as doxazosin are indicated for the treatment of patients with lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia (BPH). ED and LUTS/BPH are conditions that are often associated. Accordingly, alpha1-adrenoceptor antagonists and PDE5 inhibitors will be often prescribed in real life setting together.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1743-6109
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pubmed:author |
pubmed-author:AlexandreLaurentL,
pubmed-author:Behr-RousselDelphineD,
pubmed-author:DenouxYvesY,
pubmed-author:FaixAntoineA,
pubmed-author:GiulianoFrançoisF,
pubmed-author:GornyDianeD,
pubmed-author:LebretThierryT,
pubmed-author:LecozOlivierO,
pubmed-author:LericheAlbertA,
pubmed-author:OgerStéphanieS,
pubmed-author:WaymanChrisC
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pubmed:issnType |
Electronic
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
836-47
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:19143907-Adrenergic alpha-Antagonists,
pubmed-meshheading:19143907-Adult,
pubmed-meshheading:19143907-Doxazosin,
pubmed-meshheading:19143907-Drug Combinations,
pubmed-meshheading:19143907-Erectile Dysfunction,
pubmed-meshheading:19143907-Humans,
pubmed-meshheading:19143907-Male,
pubmed-meshheading:19143907-Muscle, Smooth,
pubmed-meshheading:19143907-Muscle Relaxation,
pubmed-meshheading:19143907-Penile Erection,
pubmed-meshheading:19143907-Penis,
pubmed-meshheading:19143907-Phosphodiesterase 5 Inhibitors,
pubmed-meshheading:19143907-Phosphodiesterase Inhibitors,
pubmed-meshheading:19143907-Piperazines,
pubmed-meshheading:19143907-Prostate,
pubmed-meshheading:19143907-Purines,
pubmed-meshheading:19143907-Sulfones
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pubmed:year |
2009
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pubmed:articleTitle |
Combination of doxazosin and sildenafil exerts an additive relaxing effect compared with each compound alone on human cavernosal and prostatic tissue.
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pubmed:affiliation |
Pelvipharm, Orsay Parc, Orsay, France.
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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