rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2009-1-15
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pubmed:abstractText |
The Major Histocompatibility Complex (MHC) region on chromosome 6p21 (IDDM1) contributes about half of the familial clustering of type 1 diabetes (T1D). Several studies have revealed that highly polymorphic genes within the MHC may associate with the mating choice. Our study should determine whether a specific mating effect is detectable in T1D families as a function of human leucocyte antigen (HLA) DR-DQ, which could contribute to disease susceptibility.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19143819-1032893,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19143819-1079575,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19143819-11713527,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19143819-15034552,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19143819-15528444,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19143819-15530631,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19143819-16027037,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19143819-16094301,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19143819-16337283,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19143819-16493429,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19143819-16879954,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19143819-3574476
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1463-1326
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
11 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
84-7
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pubmed:dateRevised |
2011-9-26
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pubmed:meshHeading |
pubmed-meshheading:19143819-Chromosomes, Human, Pair 6,
pubmed-meshheading:19143819-Diabetes Mellitus, Type 1,
pubmed-meshheading:19143819-Genetic Predisposition to Disease,
pubmed-meshheading:19143819-Genotype,
pubmed-meshheading:19143819-HLA-DQ Antigens,
pubmed-meshheading:19143819-HLA-DR Antigens,
pubmed-meshheading:19143819-Haplotypes,
pubmed-meshheading:19143819-Heterozygote,
pubmed-meshheading:19143819-Humans,
pubmed-meshheading:19143819-Sexual Behavior,
pubmed-meshheading:19143819-Time Factors
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pubmed:year |
2009
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pubmed:articleTitle |
Mating in parents of type 1 diabetes families as a function of the HLA DR-DQ haplotype.
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pubmed:affiliation |
Division of Endocrinology and Department of Immunohaematology, University Hospital Frankfurt, Frankfurt, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Research Support, N.I.H., Extramural
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