|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2009-2-9
|
|
pubmed:abstractText |
The maintenance mechanisms of peripheral tolerance by CD4(+)CD25(+) T cells before the development of sialoadenitis in secondary Sjögren's syndrome (sSS) are not well understood. The aim of the present study is to examine the effect of reduction of CD4(+)CD25(+) T cells on the development of sialoadenitis during the early life in female NZB x NZWF(1) (B/WF(1)) mice, a model for human sSS.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
D
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
1600-0714
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
38
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
234-40
|
|
pubmed:meshHeading |
pubmed-meshheading:19141059-Animals,
pubmed-meshheading:19141059-Animals, Newborn,
pubmed-meshheading:19141059-Antibodies, Antinuclear,
pubmed-meshheading:19141059-Antibodies, Monoclonal,
pubmed-meshheading:19141059-Autoantibodies,
pubmed-meshheading:19141059-Autoantigens,
pubmed-meshheading:19141059-CD4-Positive T-Lymphocytes,
pubmed-meshheading:19141059-Disease Models, Animal,
pubmed-meshheading:19141059-Female,
pubmed-meshheading:19141059-Interleukin-2 Receptor alpha Subunit,
pubmed-meshheading:19141059-Lupus Erythematosus, Systemic,
pubmed-meshheading:19141059-Mice,
pubmed-meshheading:19141059-Mice, Inbred NZB,
pubmed-meshheading:19141059-Mice, Mutant Strains,
pubmed-meshheading:19141059-Sialadenitis,
pubmed-meshheading:19141059-Sjogren's Syndrome,
pubmed-meshheading:19141059-Submandibular Gland,
pubmed-meshheading:19141059-Submandibular Gland Diseases
|
|
pubmed:year |
2009
|
|
pubmed:articleTitle |
Systemic treatment of anti-CD4CD25 T cell monoclonal antibody exacerbates sialoadenitis in submandibular glands during the early life in lupus-prone female NZB x NZWF mice.
|
|
pubmed:affiliation |
Laboratory of Veterinary Pathology, Faculty of Agriculture, Yamaguchi University, Yoshida, Yamaguchi, Japan. hayasi@yamaguchi-u.ac.jp
|
|
pubmed:publicationType |
Journal Article
|
