Linked Life Data

19139900

Source:http://linkedlifedata.com/resource/pubmed/id/19139900

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2009-1-22
pubmed:abstractText
For the last 8 years vital dyes have been used to visualize preretinal semitransparent structures in the eye during vitroretinal surgery. However, indocyanine green (ICG), which was the first commonly used dye, proved to be partly toxic to retinal cells and the retinal pigment epithelium in various in vitro and in vivo studies. Therefore, an intensive search for new and safer dyes was started. At present three dyes, trypan blue, patent blue and brilliant blue are predominantly used for vitreoretinal surgery, in addition to ICG. In this article an overview of preclinical biocompatibility studies for common vital dyes is presented. Additionally, a systematic approach for testing of new candidate dyes for vitreoretinal surgery will be proposed.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1433-0423
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
106
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
11-5
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
[Biocompatibility of dyes for vitreoretinal surgery].
pubmed:affiliation
Department für Augenheilkunde, Eberhard-Karls-Universität, Tübingen, Deutschland. sebastian.thaler@uni-tuebingen.de
pubmed:publicationType
Journal Article, English Abstract, Review