Linked Life Data

19138898

Source:http://linkedlifedata.com/resource/pubmed/id/19138898

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2009-1-13
pubmed:abstractText
Intercellular communication is fundamental in many biological processes involved in cell growth, differentiation, development, and reproduction of living organisms and secretory proteins are among the most important messengers in this network of information. The vast majority of extracellular proteins are exported from cells by the endoplasmic reticulum/Golgi-dependent secretory pathway. However, increasing evidence shows that there are a group of secretory proteins without signal peptides, defined as nonclassical secretory proteins, which are exported via an ER/Golgi-independent pathway to perform extracellular functions. This pathway has been termed nonclassical or unconventional secretion, which is an essential and beneficial supplement of the ER-Golgi secretion pathway. The nonclassical secretion pathway has close relation with cell multiplication, immune response, tumor formation, infection pathology and so on. Here, the characters, the possible secretory mechanism, and the biological significance of nonclassical secretory proteins were reviewed.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0253-9772
pubmed:author
pubmed:issnType
Print
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
29-35
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
[Nonclassical mechanisms of secretory protein in eukaryotic cells].
pubmed:affiliation
College of Life Sciences, Liaoning Normal University, Dalian 116029, China. zhangnannan_1111@163.com
pubmed:publicationType
Journal Article, English Abstract, Review