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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2009-1-12
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pubmed:abstractText |
Natural killer (NK) cells participate in pig-to-primate xenograft rejection both by antibody-dependent and -independent mechanisms. A majority of human NK cells express the inhibitory receptor CD94/NKG2A, which binds specifically to human leukocyte antigen (HLA)-E, a trimeric complex consisting of the HLA-E heavy chain, beta2-microglobulin (beta2m), and a peptide derived from the leader sequence of some major histocompatibility complex class I molecules.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1534-6080
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pubmed:author |
pubmed-author:BremGottfriedG,
pubmed-author:HerbachNadjaN,
pubmed-author:KesslerBarbaraB,
pubmed-author:LilienfeldBenjamin GBG,
pubmed-author:MüllerElfriedeE,
pubmed-author:MüllerSigridS,
pubmed-author:SchwinzerReinhardR,
pubmed-author:SeebachJörg DJD,
pubmed-author:WankeRüdigerR,
pubmed-author:WeissElisabeth HEH,
pubmed-author:WolfEckhardE
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pubmed:issnType |
Electronic
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pubmed:day |
15
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pubmed:volume |
87
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
35-43
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pubmed:meshHeading |
pubmed-meshheading:19136889-Animals,
pubmed-meshheading:19136889-Animals, Genetically Modified,
pubmed-meshheading:19136889-Cell Movement,
pubmed-meshheading:19136889-Cells, Cultured,
pubmed-meshheading:19136889-Cytotoxicity, Immunologic,
pubmed-meshheading:19136889-Endothelial Cells,
pubmed-meshheading:19136889-HLA Antigens,
pubmed-meshheading:19136889-Histocompatibility Antigens Class I,
pubmed-meshheading:19136889-Humans,
pubmed-meshheading:19136889-Killer Cells, Natural,
pubmed-meshheading:19136889-Organ Specificity,
pubmed-meshheading:19136889-Swine,
pubmed-meshheading:19136889-Transplantation, Heterologous,
pubmed-meshheading:19136889-beta 2-Microglobulin
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pubmed:year |
2009
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pubmed:articleTitle |
HLA-E/human beta2-microglobulin transgenic pigs: protection against xenogeneic human anti-pig natural killer cell cytotoxicity.
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pubmed:affiliation |
Department of Biology II, Anthropology and Human Genetics, LMU Munich, Planegg-Martinsried, Germany. Elisabeth.Weiss@lmu.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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