Linked Life Data

1913482

Source:http://linkedlifedata.com/resource/pubmed/id/1913482

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1991-11-12
pubmed:abstractText
The distribution of different malignant tumors was studied in 40 cancer family syndrome (CFS) families with 315 affected family members and a total of 472 separate tumors or malignant diseases. Only families with three or more first-degree family members with colorectal carcinoma were included and other CFS characteristics were required in at least two cases. Colorectal (63%), endometrial (8%), gastric (6%), biliopancreatic (4%), and uroepithelial carcinomas (2%) were the most frequent, and represent the tumors typical of CFS. Families with endometrial cancer (23, 57%) and those without endometrial cancer (17, 43%) did not differ in frequencies of other extracolonic carcinomas. Families with endometrial cancer has more affected members and especially more affected female members than those without endometrial cancer (means, 9.7 and 4.9 versus 5.5 and 1.6 per family, respectively). The authors conclude, therefore, that the occurrence of one or more types of extracolonic tumors in members of CFS families does not provide a firm basis for subdividing the CFS (or hereditary nonpolyposis colorectal carcinoma syndrome.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0008-543X
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
68
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1109-12
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Tumor spectrum in cancer family syndrome (hereditary nonpolyposis colorectal cancer).
pubmed:affiliation
Department of Surgery, Jyväskylä Central Hospital, Finland.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't