Linked Life Data

19132541

Source:http://linkedlifedata.com/resource/pubmed/id/19132541

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2009-7-29
pubmed:abstractText
Cupriavidus metallidurans CH34 genome contains an ortholog of Atm1p named AtmA (Rmet_0391, YP_582546). In Saccharomyces cerevisiae, the ABC-type transport system Atm1p is involved in export of iron-sulfur clusters from mitochondria into the cytoplasm for assembly of cytoplasmic iron-sulfur containing proteins. An atmA mutant of C. metallidurans was sensitive to nickel and cobalt but not iron cations. AtmA increased also resistance to these cations in Escherichia coli strains that carry deletions of the genes for other nickel and cobalt transport systems. In C. metallidurans, atmA expression was not significantly induced by nickel and cobalt, but repressed by zinc. AtmA was purified as a 70 kDa protein after expression in E. coli. ATPase activity of AtmA was stimulated by nickel and cobalt.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1572-9699
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
96
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
183-91
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
The ABC-transporter AtmA is involved in nickel and cobalt resistance of Cupriavidus metallidurans strain CH34.
pubmed:affiliation
Life Science Faculty, Institute for Biology, Martin-Luther-University Halle-Wittenberg, Kurt-Mothes-Str. 3, 06099, Halle, Germany.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't