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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2009-5-21
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pubmed:abstractText |
CD2-associated protein (CD2AP) is a crucial protein for the slit-diaphragm assembly and function. In spite of the fact that CD2AP knockout causes nephrotic syndrome in mice and the heterozygous +/- mouse is prone to proteinuria, little is known about the relevance of this molecule in human renal pathology.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1460-2385
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1858-64
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pubmed:meshHeading |
pubmed-meshheading:19131354-Adaptor Proteins, Signal Transducing,
pubmed-meshheading:19131354-Amino Acid Sequence,
pubmed-meshheading:19131354-Amino Acid Substitution,
pubmed-meshheading:19131354-Animals,
pubmed-meshheading:19131354-Antigens, CD2,
pubmed-meshheading:19131354-Apoptosis,
pubmed-meshheading:19131354-Base Sequence,
pubmed-meshheading:19131354-Case-Control Studies,
pubmed-meshheading:19131354-Child, Preschool,
pubmed-meshheading:19131354-Cytoskeletal Proteins,
pubmed-meshheading:19131354-DNA,
pubmed-meshheading:19131354-Female,
pubmed-meshheading:19131354-Glomerulosclerosis, Focal Segmental,
pubmed-meshheading:19131354-Humans,
pubmed-meshheading:19131354-Male,
pubmed-meshheading:19131354-Mice,
pubmed-meshheading:19131354-Mice, Knockout,
pubmed-meshheading:19131354-Molecular Sequence Data,
pubmed-meshheading:19131354-Mutation,
pubmed-meshheading:19131354-Mutation, Missense,
pubmed-meshheading:19131354-Nephrotic Syndrome,
pubmed-meshheading:19131354-Sequence Deletion,
pubmed-meshheading:19131354-Sequence Homology, Amino Acid,
pubmed-meshheading:19131354-T-Lymphocytes,
pubmed-meshheading:19131354-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
CD2AP mutations are associated with sporadic nephrotic syndrome and focal segmental glomerulosclerosis (FSGS).
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pubmed:affiliation |
Department of Biomedical Sciences, University of Foggia, Genoa, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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