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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2009-6-22
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pubmed:abstractText |
Low high-density lipoprotein cholesterol (HDL-C) serum concentrations are independent risk factors for the development of coronary artery disease. In patients with the metabolic syndrome, low HDL-C can contribute to premature atherosclerosis. Extended-release (ER) niacin increases HDL-C and was shown to slow the progression of atherosclerosis. Adipose tissue is an important site of niacin action. Here we sought to determine potential pleiotropic effects of ER niacin on adipose tissue biology in patients with impaired glucose tolerance (IGT).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1879-1484
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
205
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
207-13
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:19131065-Adipocytes,
pubmed-meshheading:19131065-Adipose Tissue,
pubmed-meshheading:19131065-Adult,
pubmed-meshheading:19131065-Cholesterol, HDL,
pubmed-meshheading:19131065-Cholesterol, LDL,
pubmed-meshheading:19131065-Delayed-Action Preparations,
pubmed-meshheading:19131065-Disease Progression,
pubmed-meshheading:19131065-Female,
pubmed-meshheading:19131065-Gene Expression Profiling,
pubmed-meshheading:19131065-Glucose,
pubmed-meshheading:19131065-Humans,
pubmed-meshheading:19131065-Hypolipidemic Agents,
pubmed-meshheading:19131065-Lipids,
pubmed-meshheading:19131065-Male,
pubmed-meshheading:19131065-Middle Aged,
pubmed-meshheading:19131065-Niacin,
pubmed-meshheading:19131065-Risk Factors
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pubmed:year |
2009
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pubmed:articleTitle |
Effects of extended-release niacin on lipid profile and adipocyte biology in patients with impaired glucose tolerance.
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pubmed:affiliation |
Department of Cardiology, Heart Center, University of Leipzig, Leipzig, Germany.
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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