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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1991-11-8
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pubmed:abstractText |
Forty patients with rheumatoid arthritis and upper gastrointestinal lesions due to non-steroidal anti-inflammatory drugs entered a prospective 6-month double-blind placebo controlled study of dietary supplementation with gamma-linolenic acid 540 mg/day. Nineteen patients received active therapy (as evening primrose oil 6 g/day) and 21 received placebo (olive oil 6 g/day). No patient stopped non-steroidal anti-inflammatory therapy but three patients in each group reduced their dose. Other results showed a significant reduction in morning stiffness with gamma-linolenic acid at 3 months and reduction in pain and articular index at 6 months with olive oil. Whilst gamma-linolenic acid may produce mild improvement in rheumatoid arthritis, olive oil may itself have hitherto unrecognized benefits.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0263-7103
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
370-2
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1913008-Adolescent,
pubmed-meshheading:1913008-Adult,
pubmed-meshheading:1913008-Aged,
pubmed-meshheading:1913008-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:1913008-Arthritis, Rheumatoid,
pubmed-meshheading:1913008-Double-Blind Method,
pubmed-meshheading:1913008-Fatty Acids, Essential,
pubmed-meshheading:1913008-Female,
pubmed-meshheading:1913008-Gastritis,
pubmed-meshheading:1913008-Humans,
pubmed-meshheading:1913008-Linoleic Acids,
pubmed-meshheading:1913008-Male,
pubmed-meshheading:1913008-Middle Aged,
pubmed-meshheading:1913008-Peptic Ulcer,
pubmed-meshheading:1913008-Plant Oils,
pubmed-meshheading:1913008-Prospective Studies,
pubmed-meshheading:1913008-gamma-Linolenic Acid
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pubmed:year |
1991
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pubmed:articleTitle |
Evening primrose oil in patients with rheumatoid arthritis and side-effects of non-steroidal anti-inflammatory drugs.
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pubmed:affiliation |
University Department of Medicine, Royal Infirmary, Glasgow.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
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