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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2009-2-9
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pubmed:abstractText |
The molecular mechanisms that underlie colorectal cancer (CRC) include microsatellite instability (MSI), chromosomal instability, and the CpG island methylator phenotype. There is evidence to suggest that CRC incidence varies among different ethnic populations worldwide. The authors of this report hypothesized that environmental factors and lifestyle differences among various ethnic groups may differentially influence the epigenetic regulation of tumor suppressor genes in CRC.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-10232580,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-10411935,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-10639144,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-11197253,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-11729109,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-12068308,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-12198537,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-12454837,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-12469762,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-14639609,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-14652271,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-14762775,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-14970275,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-15340260,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-15342696,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-15516843,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-15542810,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-16143123,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-16739315,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-16804544,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-17087942,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-17148775,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-17301300,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-17465465,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-8482467,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-8484121,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-8484122,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-9121588,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-9288102,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19127559-9618505
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0008-543X
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pubmed:author |
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pubmed:copyrightInfo |
(c) 2009 American Cancer Society.
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
115
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
760-9
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pubmed:dateRevised |
2011-9-26
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pubmed:meshHeading |
pubmed-meshheading:19127559-Adaptor Proteins, Signal Transducing,
pubmed-meshheading:19127559-Aged,
pubmed-meshheading:19127559-Arabs,
pubmed-meshheading:19127559-Colorectal Neoplasms,
pubmed-meshheading:19127559-CpG Islands,
pubmed-meshheading:19127559-DNA Methylation,
pubmed-meshheading:19127559-DNA Mutational Analysis,
pubmed-meshheading:19127559-Female,
pubmed-meshheading:19127559-Humans,
pubmed-meshheading:19127559-Immunoenzyme Techniques,
pubmed-meshheading:19127559-Israel,
pubmed-meshheading:19127559-Jews,
pubmed-meshheading:19127559-Male,
pubmed-meshheading:19127559-Microsatellite Instability,
pubmed-meshheading:19127559-Mutation,
pubmed-meshheading:19127559-Nuclear Proteins,
pubmed-meshheading:19127559-Phenotype,
pubmed-meshheading:19127559-Polymerase Chain Reaction,
pubmed-meshheading:19127559-Promoter Regions, Genetic,
pubmed-meshheading:19127559-Proto-Oncogene Proteins B-raf
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pubmed:year |
2009
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pubmed:articleTitle |
Microsatellite instability, MLH1 promoter methylation, and BRAF mutation analysis in sporadic colorectal cancers of different ethnic groups in Israel.
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pubmed:affiliation |
Department of Gastroenterology, Rabin Medical Center, Beilinson Hospital, Tel Aviv University, Tel Aviv, Israel.
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pubmed:publicationType |
Journal Article
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