We develop a multiplex quantitative real-time PCR for synchronized analysis of mitochondrial DNA (mtDNA) and nuclear DNA (nDNA) to investigate relative mtDNA abundance in paired normal and cancerous breast tissues.
Laboratory for Prenatal Medicine and Gynecologic Oncology, Department of Biomedicine, Women's Hospital, University of Basel, Hebelstrasse 20, Room Nr. 416, 4031 Basel, Switzerland.